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Effect of maturation on the composition and biological activity of the essential oil of a commercially important Satureja species from Turkey: Satureja cuneifolia Ten. (Lamiaceae).
J Agric Food Chem. 2008 Mar 26; 56(6):2260-5.JA

Abstract

The essential oil obtained by hydrodistillation from aerial parts of Satureja cuneifolia Ten., collected in three different maturation stages such as preflowering, flowering, and postflowering, were analyzed simultaneously by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Thymol (42.5-45.2%), p-cymene (19.4-24.3%), and carvacrol (8.5-13.2%) were identified as the main constituent in all stages. At the same time, the essential oils and main components were evaluated for their antimicrobial activity using a microdilution assay resulting in the inhibition of a number of common human pathogenic bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and the yeasts Candida albicans and Candida tropicalis. The minimum inhibitory concentrations (MIC) varied between 62.5 and 250 microg/mL within a moderate antimicrobial activity range. Furthermore, the antioxidant capacity of the essential oils and major components thymol and carvacrol were examined in vitro. The essential oils obtained from S. cuneifolia in three different stages and its main components were interacted with 1,1-diphenyl-2-picrylhydrazyl (DPPH (*)) as a nitrogen-centered stable radical, resulting in IC 50 = 1.6-2.1 mg/mL. In addition, the effects on inhibition of lipid peroxidation of the essential oils were assayed using the beta-carotene bleaching method. All of the tested oils inhibited the linoleic acid peroxidation at almost the same level as butylated hydroxytoluene (BHT) (93.54-94.65%). BHT and ascorbic acid were used as positive controls in the antioxidant assays.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Koşar M
Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey. mkosar@anadolu.edu.tr
Demirci B
No affiliation info available
Demirci F
No affiliation info available
Başer KH
No affiliation info available

MeSH

Anti-Infective AgentsBacteriaCandidaChromatography, GasCyclohexane MonoterpenesCymenesGas Chromatography-Mass SpectrometryMonoterpenesOils, VolatileSaturejaThymolTurkey

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18290618

Citation

Koşar, Müberra, et al. "Effect of Maturation On the Composition and Biological Activity of the Essential Oil of a Commercially Important Satureja Species From Turkey: Satureja Cuneifolia Ten. (Lamiaceae)." Journal of Agricultural and Food Chemistry, vol. 56, no. 6, 2008, pp. 2260-5.
Koşar M, Demirci B, Demirci F, et al. Effect of maturation on the composition and biological activity of the essential oil of a commercially important Satureja species from Turkey: Satureja cuneifolia Ten. (Lamiaceae). J Agric Food Chem. 2008;56(6):2260-5.
Koşar, M., Demirci, B., Demirci, F., & Başer, K. H. (2008). Effect of maturation on the composition and biological activity of the essential oil of a commercially important Satureja species from Turkey: Satureja cuneifolia Ten. (Lamiaceae). Journal of Agricultural and Food Chemistry, 56(6), 2260-5. https://doi.org/10.1021/jf0732253
Koşar M, et al. Effect of Maturation On the Composition and Biological Activity of the Essential Oil of a Commercially Important Satureja Species From Turkey: Satureja Cuneifolia Ten. (Lamiaceae). J Agric Food Chem. 2008 Mar 26;56(6):2260-5. PubMed PMID: 18290618.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of maturation on the composition and biological activity of the essential oil of a commercially important Satureja species from Turkey: Satureja cuneifolia Ten. (Lamiaceae). AU - Koşar,Müberra, AU - Demirci,Betül, AU - Demirci,Fatih, AU - Başer,K Hüsnü Can, Y1 - 2008/02/22/ PY - 2008/2/23/pubmed PY - 2008/6/12/medline PY - 2008/2/23/entrez SP - 2260 EP - 5 JF - Journal of agricultural and food chemistry JO - J Agric Food Chem VL - 56 IS - 6 N2 - The essential oil obtained by hydrodistillation from aerial parts of Satureja cuneifolia Ten., collected in three different maturation stages such as preflowering, flowering, and postflowering, were analyzed simultaneously by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Thymol (42.5-45.2%), p-cymene (19.4-24.3%), and carvacrol (8.5-13.2%) were identified as the main constituent in all stages. At the same time, the essential oils and main components were evaluated for their antimicrobial activity using a microdilution assay resulting in the inhibition of a number of common human pathogenic bacteria including methicillin-resistant Staphylococcus aureus (MRSA) and the yeasts Candida albicans and Candida tropicalis. The minimum inhibitory concentrations (MIC) varied between 62.5 and 250 microg/mL within a moderate antimicrobial activity range. Furthermore, the antioxidant capacity of the essential oils and major components thymol and carvacrol were examined in vitro. The essential oils obtained from S. cuneifolia in three different stages and its main components were interacted with 1,1-diphenyl-2-picrylhydrazyl (DPPH (*)) as a nitrogen-centered stable radical, resulting in IC 50 = 1.6-2.1 mg/mL. In addition, the effects on inhibition of lipid peroxidation of the essential oils were assayed using the beta-carotene bleaching method. All of the tested oils inhibited the linoleic acid peroxidation at almost the same level as butylated hydroxytoluene (BHT) (93.54-94.65%). BHT and ascorbic acid were used as positive controls in the antioxidant assays. SN - 0021-8561 UR - https://www.unboundmedicine.com/medline/citation/18290618/Effect_of_maturation_on_the_composition_and_biological_activity_of_the_essential_oil_of_a_commercially_important_Satureja_species_from_Turkey:_Satureja_cuneifolia_Ten___Lamiaceae__ DB - PRIME DP - Unbound Medicine ER -