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Neoadjuvant therapy in a patient with clival plasmacytoma associated with multiple myeloma: a case report.
Surg Neurol. 2008 Oct; 70(4):403-7.SN

Abstract

BACKGROUND

Plasmacytoma is a localized mass of metastatic plasma cells. These lesions rarely involve the petroclival region and carry a high risk of progression to MM and poor prognosis.

CASE DESCRIPTION

We report a 65-year-old woman who presented with a large clival plasmacytoma causing right trigeminal and abducens nerve palsies and was diagnosed with MM after transsphenoidal biopsy. She underwent neoadjuvant chemoradiotherapy followed by radical resection of the residual tumor.

CONCLUSION

We presented our treatment strategy including neoadjuvant chemoradiotherapy followed by radical resection of the lesion. The patient has experienced complete remission, and succeeding MRI revealed no evidence of local recurrence.

Authors+Show Affiliations

Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo 060-8638, Japan. syamama1945@yahoo.co.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18291467

Citation

Yamaguchi, Shigeru, et al. "Neoadjuvant Therapy in a Patient With Clival Plasmacytoma Associated With Multiple Myeloma: a Case Report." Surgical Neurology, vol. 70, no. 4, 2008, pp. 403-7.
Yamaguchi S, Terasaka S, Ando S, et al. Neoadjuvant therapy in a patient with clival plasmacytoma associated with multiple myeloma: a case report. Surg Neurol. 2008;70(4):403-7.
Yamaguchi, S., Terasaka, S., Ando, S., Shinohara, T., & Iwasaki, Y. (2008). Neoadjuvant therapy in a patient with clival plasmacytoma associated with multiple myeloma: a case report. Surgical Neurology, 70(4), 403-7. https://doi.org/10.1016/j.surneu.2007.10.020
Yamaguchi S, et al. Neoadjuvant Therapy in a Patient With Clival Plasmacytoma Associated With Multiple Myeloma: a Case Report. Surg Neurol. 2008;70(4):403-7. PubMed PMID: 18291467.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Neoadjuvant therapy in a patient with clival plasmacytoma associated with multiple myeloma: a case report. AU - Yamaguchi,Shigeru, AU - Terasaka,Shunsuke, AU - Ando,Sachiko, AU - Shinohara,Toshiya, AU - Iwasaki,Yoshinobu, Y1 - 2008/03/04/ PY - 2007/06/05/received PY - 2007/10/09/accepted PY - 2008/2/23/pubmed PY - 2008/11/14/medline PY - 2008/2/23/entrez SP - 403 EP - 7 JF - Surgical neurology JO - Surg Neurol VL - 70 IS - 4 N2 - BACKGROUND: Plasmacytoma is a localized mass of metastatic plasma cells. These lesions rarely involve the petroclival region and carry a high risk of progression to MM and poor prognosis. CASE DESCRIPTION: We report a 65-year-old woman who presented with a large clival plasmacytoma causing right trigeminal and abducens nerve palsies and was diagnosed with MM after transsphenoidal biopsy. She underwent neoadjuvant chemoradiotherapy followed by radical resection of the residual tumor. CONCLUSION: We presented our treatment strategy including neoadjuvant chemoradiotherapy followed by radical resection of the lesion. The patient has experienced complete remission, and succeeding MRI revealed no evidence of local recurrence. SN - 0090-3019 UR - https://www.unboundmedicine.com/medline/citation/18291467/Neoadjuvant_therapy_in_a_patient_with_clival_plasmacytoma_associated_with_multiple_myeloma:_a_case_report_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0090-3019(07)01258-X DB - PRIME DP - Unbound Medicine ER -