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Antimicrobial triterpenoids from Vladimiria muliensis.
J Nat Prod. 2008 Apr; 71(4):547-50.JN

Abstract

A new triterpenoid with a rearranged ursane skeleton, 3beta-acetoxyl-11alpha-methoxybauer-8-en-7alpha-ol (1), two new ursane triterpenoids, 1alpha,5alpha-dioxy-11alpha-hydroxyurs-12-en-3-one (2) and urs-3beta,13alpha,18beta-triol (3), together with three known ursane triterpenoids (4- 6) were isolated from the rhizome of Vladimiria muliensis. Their structures were elucidated on the basis of spectroscopic methods (IR, EIMS, HRESIMS, 1D and 2D NMR, and X-ray crystallography diffraction). Compounds 2 and 4 exhibited modest antimicrobial activity against Escherichia coli, Candida albicans, Pseudomonas aeruginosa, Enterococcus faecalis, Bacillus cereus, and Staphylococcus aureus.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Chen JJ
State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, People's Republic of China.
Fei DQ
No affiliation info available
Chen SG
No affiliation info available
Gao K
No affiliation info available

MeSH

Anti-Infective AgentsAsteraceaeBacillus cereusCandida albicansDrugs, Chinese HerbalEnterococcus faecalisEscherichia coliMicrobial Sensitivity TestsMolecular StructurePlants, MedicinalPseudomonas aeruginosaRhizomeStaphylococcus aureusTriterpenes

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18293903

Citation

Chen, Jian-Jun, et al. "Antimicrobial Triterpenoids From Vladimiria Muliensis." Journal of Natural Products, vol. 71, no. 4, 2008, pp. 547-50.
Chen JJ, Fei DQ, Chen SG, et al. Antimicrobial triterpenoids from Vladimiria muliensis. J Nat Prod. 2008;71(4):547-50.
Chen, J. J., Fei, D. Q., Chen, S. G., & Gao, K. (2008). Antimicrobial triterpenoids from Vladimiria muliensis. Journal of Natural Products, 71(4), 547-50. https://doi.org/10.1021/np070483l
Chen JJ, et al. Antimicrobial Triterpenoids From Vladimiria Muliensis. J Nat Prod. 2008;71(4):547-50. PubMed PMID: 18293903.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial triterpenoids from Vladimiria muliensis. AU - Chen,Jian-Jun, AU - Fei,Dong-Qing, AU - Chen,Sheng-Gao, AU - Gao,Kun, Y1 - 2008/02/23/ PY - 2008/2/26/pubmed PY - 2008/6/14/medline PY - 2008/2/26/entrez SP - 547 EP - 50 JF - Journal of natural products JO - J Nat Prod VL - 71 IS - 4 N2 - A new triterpenoid with a rearranged ursane skeleton, 3beta-acetoxyl-11alpha-methoxybauer-8-en-7alpha-ol (1), two new ursane triterpenoids, 1alpha,5alpha-dioxy-11alpha-hydroxyurs-12-en-3-one (2) and urs-3beta,13alpha,18beta-triol (3), together with three known ursane triterpenoids (4- 6) were isolated from the rhizome of Vladimiria muliensis. Their structures were elucidated on the basis of spectroscopic methods (IR, EIMS, HRESIMS, 1D and 2D NMR, and X-ray crystallography diffraction). Compounds 2 and 4 exhibited modest antimicrobial activity against Escherichia coli, Candida albicans, Pseudomonas aeruginosa, Enterococcus faecalis, Bacillus cereus, and Staphylococcus aureus. SN - 0163-3864 UR - https://www.unboundmedicine.com/medline/citation/18293903/Antimicrobial_triterpenoids_from_Vladimiria_muliensis_ DB - PRIME DP - Unbound Medicine ER -