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Aquaporin 1 expression in the testis, epididymis and vas deferens of postnatal ICR mice.
Cell Biol Int. 2008 May; 32(5):532-41.CB

Abstract

Aquaporin 1 (AQP1) is one of the water channels involved in water transfer and reabsorption. The results of a reverse transcription-polymerase chain reaction (RT-PCR) indicated that the level of AQP1 mRNA was increased in the testis and vas deferens, but decreased in the epididymis from the early postnatal period through puberty to adulthood. The results of Western blot analyses largely matched the RT-PCR findings for AQP1. AQP1 was immunohistochemically localized on the plasma membrane in the epithelia of rete testis and vas deferens at postnatal day 70, although it was hardly detectable at postnatal day 15. Nevertheless, AQP1 was expressed in the epithelia of the efferent duct and the initial segment of caput epididymis at postnatal day 15 and persisted into adulthood. The results taken together suggest that the expression and localization of AQP1 in mouse testis, epididymis and vas deferens are a stage-, tissue- and region-specific pattern and provide obvious clues that a possible relationship exists between the functional application of AQP1 for water reabsorption, and male reproduction and maturation.

Authors+Show Affiliations

Department of Anatomy & Histology and Embryology, Peking University Health Science Center, Beijing 100083, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18296079

Citation

Danyu, Lu, et al. "Aquaporin 1 Expression in the Testis, Epididymis and Vas Deferens of Postnatal ICR Mice." Cell Biology International, vol. 32, no. 5, 2008, pp. 532-41.
Danyu L, Ying L, Zhenwu B, et al. Aquaporin 1 expression in the testis, epididymis and vas deferens of postnatal ICR mice. Cell Biol Int. 2008;32(5):532-41.
Danyu, L., Ying, L., Zhenwu, B., Heming, Y., & Xuejun, L. (2008). Aquaporin 1 expression in the testis, epididymis and vas deferens of postnatal ICR mice. Cell Biology International, 32(5), 532-41. https://doi.org/10.1016/j.cellbi.2008.01.002
Danyu L, et al. Aquaporin 1 Expression in the Testis, Epididymis and Vas Deferens of Postnatal ICR Mice. Cell Biol Int. 2008;32(5):532-41. PubMed PMID: 18296079.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Aquaporin 1 expression in the testis, epididymis and vas deferens of postnatal ICR mice. AU - Danyu,Lu, AU - Ying,Li, AU - Zhenwu,Bi, AU - Heming,Yu, AU - Xuejun,Li, Y1 - 2008/01/25/ PY - 2007/06/22/received PY - 2007/11/28/revised PY - 2008/01/14/accepted PY - 2008/2/26/pubmed PY - 2008/8/9/medline PY - 2008/2/26/entrez SP - 532 EP - 41 JF - Cell biology international JO - Cell Biol Int VL - 32 IS - 5 N2 - Aquaporin 1 (AQP1) is one of the water channels involved in water transfer and reabsorption. The results of a reverse transcription-polymerase chain reaction (RT-PCR) indicated that the level of AQP1 mRNA was increased in the testis and vas deferens, but decreased in the epididymis from the early postnatal period through puberty to adulthood. The results of Western blot analyses largely matched the RT-PCR findings for AQP1. AQP1 was immunohistochemically localized on the plasma membrane in the epithelia of rete testis and vas deferens at postnatal day 70, although it was hardly detectable at postnatal day 15. Nevertheless, AQP1 was expressed in the epithelia of the efferent duct and the initial segment of caput epididymis at postnatal day 15 and persisted into adulthood. The results taken together suggest that the expression and localization of AQP1 in mouse testis, epididymis and vas deferens are a stage-, tissue- and region-specific pattern and provide obvious clues that a possible relationship exists between the functional application of AQP1 for water reabsorption, and male reproduction and maturation. SN - 1065-6995 UR - https://www.unboundmedicine.com/medline/citation/18296079/Aquaporin_1_expression_in_the_testis_epididymis_and_vas_deferens_of_postnatal_ICR_mice_ L2 - https://doi.org/10.1016/j.cellbi.2008.01.002 DB - PRIME DP - Unbound Medicine ER -