TY - JOUR T1 - Migraine, stroke and patent foramen ovale: a dangerous trio? AU - Butera,Gianfranco, AU - Agostoni,Elio, AU - Biondi-Zoccai,Giuseppe, AU - Bresolin,Nereo, AU - Fumagalli,Lorenzo, AU - Chessa,Massimo, AU - Gallanti,Andrea, AU - Scacciatela,Paolo, AU - Carminati,Mario, PY - 2008/2/28/pubmed PY - 2008/5/16/medline PY - 2008/2/28/entrez SP - 233 EP - 8 JF - Journal of cardiovascular medicine (Hagerstown, Md.) JO - J Cardiovasc Med (Hagerstown) VL - 9 IS - 3 N2 - The relationship between migraine, stroke and patent foramen ovale (PFO) has been the subject of considerable research efforts. Indeed, a lot of interest has focused on the potential benefits of percutaneous PFO closure. The aim of this article is to review data from the currently available literature. A total of 10 relevant studies were found in the literature, for a total of 1038 patients undergoing percutaneous PFO closure after events of cryptogenic stroke. Thirty-eight percent of these patients suffered from migraine. Combining the results of the available studies, 72% of patients were cured or improved significantly. Analysing the results according to migraine type, 81% of patients with migraine with aura had complete resolution or significantly improved as compared to 72% of patients with migraine without aura. Several limitations and drawbacks exist, however, and they are extensively discussed in this paper. SN - 1558-2027 UR - https://www.unboundmedicine.com/medline/citation/18301138/Migraine_stroke_and_patent_foramen_ovale:_a_dangerous_trio L2 - https://doi.org/10.2459/JCM.0b013e3282058912 DB - PRIME DP - Unbound Medicine ER -