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Validation of the reflux disease questionnaire for an Italian population of patients with gastroesophageal reflux disease.
Eur J Gastroenterol Hepatol. 2008 Mar; 20(3):187-90.EJ

Abstract

BACKGROUND/AIMS

The reflux disease questionnaire (RDQ) is a very simple questionnaire based on only 12 questions that can be answered and evaluated quickly in a primary care setting, which was already found to be valid and reliable in the diagnosis of gastroesophageal reflux disease (GERD). As an English and a German version of the RDQ exist, but not an Italian one, we aimed at translating the RDQ into Italian and evaluating its reliability for the use of Italian-speaking GERD patients.

PATIENTS/METHODS

For the purpose of linguistic validation, we translated backward and forward the original RDQ into Italian and again into English. For the purpose of assessing internal consistency, test-retest, and interrater reliability, 130 GERD patients were used, of whom 57 patients had an endoscopic oesophagitis of grade A to C according to the Los Angeles classification and 63 patients had uninvestigated GERD symptoms but with a frequency of heartburn and/or regurgitation at least twice a week.

RESULTS

After professional translation, the Italian RDQ was judged to retain fully the meaning of the original RDQ. Internal consistency, as judged by the (Cronbach's alpha) was satisfactory, with an overall RDQ scale alpha=0.86 (minimum acceptable value=0.70). Test--retest reliability (Spearman coefficient) was again found to be optimal, with individual item values ranging between 0.74 (for 'pain in the upper stomach: frequency') and 0.90 (for 'burning feeling behind breastbone: severity'). Finally, the correlation coefficient was 0.96 for the total scale and a range of 0.85-0.98 for individual items, indicating extremely satisfactory concordance.

CONCLUSIONS

The Italian RDQ appears to be a simple, reproducible, and reliable tool for the diagnosis of GERD. We believe that this questionnaire is well suited for use, both in primary care settings and in epidemiological studies, in particular for the assessment of so-called typical symptoms.

Authors+Show Affiliations

Department of Clinical Sciences, Division of Gastroenterology, L Sacco University Hospital, Milan, Italy. fabio.pace@unimi.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Validation Study

Language

eng

PubMed ID

18301298

Citation

Pace, Fabio, et al. "Validation of the Reflux Disease Questionnaire for an Italian Population of Patients With Gastroesophageal Reflux Disease." European Journal of Gastroenterology & Hepatology, vol. 20, no. 3, 2008, pp. 187-90.
Pace F, Scarlata P, Casini V, et al. Validation of the reflux disease questionnaire for an Italian population of patients with gastroesophageal reflux disease. Eur J Gastroenterol Hepatol. 2008;20(3):187-90.
Pace, F., Scarlata, P., Casini, V., Sarzi-Puttini, P., & Porro, G. B. (2008). Validation of the reflux disease questionnaire for an Italian population of patients with gastroesophageal reflux disease. European Journal of Gastroenterology & Hepatology, 20(3), 187-90. https://doi.org/10.1097/MEG.0b013e3282f246b2
Pace F, et al. Validation of the Reflux Disease Questionnaire for an Italian Population of Patients With Gastroesophageal Reflux Disease. Eur J Gastroenterol Hepatol. 2008;20(3):187-90. PubMed PMID: 18301298.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Validation of the reflux disease questionnaire for an Italian population of patients with gastroesophageal reflux disease. AU - Pace,Fabio, AU - Scarlata,Pamela, AU - Casini,Valentina, AU - Sarzi-Puttini,Piercarlo, AU - Porro,Gabriele Bianchi, PY - 2008/2/28/pubmed PY - 2009/4/4/medline PY - 2008/2/28/entrez SP - 187 EP - 90 JF - European journal of gastroenterology & hepatology JO - Eur J Gastroenterol Hepatol VL - 20 IS - 3 N2 - BACKGROUND/AIMS: The reflux disease questionnaire (RDQ) is a very simple questionnaire based on only 12 questions that can be answered and evaluated quickly in a primary care setting, which was already found to be valid and reliable in the diagnosis of gastroesophageal reflux disease (GERD). As an English and a German version of the RDQ exist, but not an Italian one, we aimed at translating the RDQ into Italian and evaluating its reliability for the use of Italian-speaking GERD patients. PATIENTS/METHODS: For the purpose of linguistic validation, we translated backward and forward the original RDQ into Italian and again into English. For the purpose of assessing internal consistency, test-retest, and interrater reliability, 130 GERD patients were used, of whom 57 patients had an endoscopic oesophagitis of grade A to C according to the Los Angeles classification and 63 patients had uninvestigated GERD symptoms but with a frequency of heartburn and/or regurgitation at least twice a week. RESULTS: After professional translation, the Italian RDQ was judged to retain fully the meaning of the original RDQ. Internal consistency, as judged by the (Cronbach's alpha) was satisfactory, with an overall RDQ scale alpha=0.86 (minimum acceptable value=0.70). Test--retest reliability (Spearman coefficient) was again found to be optimal, with individual item values ranging between 0.74 (for 'pain in the upper stomach: frequency') and 0.90 (for 'burning feeling behind breastbone: severity'). Finally, the correlation coefficient was 0.96 for the total scale and a range of 0.85-0.98 for individual items, indicating extremely satisfactory concordance. CONCLUSIONS: The Italian RDQ appears to be a simple, reproducible, and reliable tool for the diagnosis of GERD. We believe that this questionnaire is well suited for use, both in primary care settings and in epidemiological studies, in particular for the assessment of so-called typical symptoms. SN - 1473-5687 UR - https://www.unboundmedicine.com/medline/citation/18301298/Validation_of_the_reflux_disease_questionnaire_for_an_Italian_population_of_patients_with_gastroesophageal_reflux_disease_ L2 - http://dx.doi.org/10.1097/MEG.0b013e3282f246b2 DB - PRIME DP - Unbound Medicine ER -