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Nocturia in Spanish patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH).
Curr Med Res Opin. 2008 Apr; 24(4):1033-8.CM

Abstract

OBJECTIVE

This study aimed to assess the prevalence of nocturia and its impact on quality of life (QoL) in Spanish patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH).

RESEARCH DESIGN AND METHODS

This was a Spanish, multicentre, cross-sectional study. Outpatients aged 60 years and over with LUTS/BPH, a prostate size > or = 25 g, untreated for LUTS/BPH and responding to the International Prostate Symptom Score (I-PSS) were included. Nocturia was defined as > or = 2 nocturnal voids/night. The Spanish version of the Nocturia-specific Quality of Life (N-QoL) questionnaire assessed the impact of nocturia on QoL, with a low score indicating a poor QoL due to nocturia.

RESULTS

A total of 502 patients were included; mean age 68.1 +/- 5.7 years, mean I-PSS 14.9 +/- 7.1, mean prostate size 50.9 +/- 20 g. The overall prevalence of nocturia was 83.1% (95% confidence interval [CI]: 79.8-86.4). Patients with nocturia had a lower score on the overall N-QoL questionnaire and the sleep/energy and bother/concern domains than those without nocturia (p < 0.001); 42.9% of patients with nocturia stated that they had a good-very good QoL compared to 90.6% in those without nocturia (p < 0.001).

CONCLUSION

This study shows a high prevalence of nocturia in Spanish LUTS/BPH patients. Nocturia negatively impacts on the QoL of LUTS/BPH patients, which is reflected in worse sleep, reduced energy levels and increased bother and concern. Therefore adequate treatment of this symptom is necessary.

Authors+Show Affiliations

Hospital Universitario Gregorio Marañón, Madrid, Spain. carloshfdez@telefonica.netNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18302812

Citation

Hernández, Carlos, et al. "Nocturia in Spanish Patients With Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (LUTS/BPH)." Current Medical Research and Opinion, vol. 24, no. 4, 2008, pp. 1033-8.
Hernández C, Estivill E, Prieto M, et al. Nocturia in Spanish patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). Curr Med Res Opin. 2008;24(4):1033-8.
Hernández, C., Estivill, E., Prieto, M., & Badía, X. (2008). Nocturia in Spanish patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). Current Medical Research and Opinion, 24(4), 1033-8. https://doi.org/10.1185/030079908X280473
Hernández C, et al. Nocturia in Spanish Patients With Lower Urinary Tract Symptoms Suggestive of Benign Prostatic Hyperplasia (LUTS/BPH). Curr Med Res Opin. 2008;24(4):1033-8. PubMed PMID: 18302812.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nocturia in Spanish patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). AU - Hernández,Carlos, AU - Estivill,Eduard, AU - Prieto,Marta, AU - Badía,Xavier, Y1 - 2008/02/25/ PY - 2008/2/28/pubmed PY - 2008/6/14/medline PY - 2008/2/28/entrez SP - 1033 EP - 8 JF - Current medical research and opinion JO - Curr Med Res Opin VL - 24 IS - 4 N2 - OBJECTIVE: This study aimed to assess the prevalence of nocturia and its impact on quality of life (QoL) in Spanish patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH). RESEARCH DESIGN AND METHODS: This was a Spanish, multicentre, cross-sectional study. Outpatients aged 60 years and over with LUTS/BPH, a prostate size > or = 25 g, untreated for LUTS/BPH and responding to the International Prostate Symptom Score (I-PSS) were included. Nocturia was defined as > or = 2 nocturnal voids/night. The Spanish version of the Nocturia-specific Quality of Life (N-QoL) questionnaire assessed the impact of nocturia on QoL, with a low score indicating a poor QoL due to nocturia. RESULTS: A total of 502 patients were included; mean age 68.1 +/- 5.7 years, mean I-PSS 14.9 +/- 7.1, mean prostate size 50.9 +/- 20 g. The overall prevalence of nocturia was 83.1% (95% confidence interval [CI]: 79.8-86.4). Patients with nocturia had a lower score on the overall N-QoL questionnaire and the sleep/energy and bother/concern domains than those without nocturia (p < 0.001); 42.9% of patients with nocturia stated that they had a good-very good QoL compared to 90.6% in those without nocturia (p < 0.001). CONCLUSION: This study shows a high prevalence of nocturia in Spanish LUTS/BPH patients. Nocturia negatively impacts on the QoL of LUTS/BPH patients, which is reflected in worse sleep, reduced energy levels and increased bother and concern. Therefore adequate treatment of this symptom is necessary. SN - 1473-4877 UR - https://www.unboundmedicine.com/medline/citation/18302812/Nocturia_in_Spanish_patients_with_lower_urinary_tract_symptoms_suggestive_of_benign_prostatic_hyperplasia__LUTS/BPH__ L2 - https://www.tandfonline.com/doi/full/10.1185/030079908x280473 DB - PRIME DP - Unbound Medicine ER -