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[Evaluation of the efficacy of wiferon and arbidol in adult influenza].
Vopr Virusol. 2008 Jan-Feb; 53(1):31-3.VV

Abstract

The therapeutic efficacy of wiferon (recombinant alpha2beta-interferon) versus arbidol was studied in a double-blind controlled study in patients with laboratorily verified influenza. Within the first 24-36 hours after the onset of the disease, wiferon and arbidol reduced the duration of fever, intoxication, and the catarrhal symptoms of the disease as a whole. The agents were shown to have an immunomodulating effect.

Authors

Kolobukhina LV
No affiliation info available
Malinovskaia VV
No affiliation info available
Gatich RZ
No affiliation info available
Merkulova LN
No affiliation info available
Burtseva EI
No affiliation info available
Isaeva EI
No affiliation info available
Parshina OV
No affiliation info available
Guseva TS
No affiliation info available
Orlova TG
No affiliation info available
Voronina FV
No affiliation info available

MeSH

Administration, RectalAdolescentAdultAntiviral AgentsCoughDouble-Blind MethodFeverHumansIndolesInfluenza, HumanInterferon alpha-2Interferon-alphaInterferonsLeukocytesLymphocyte CountMiddle AgedRecombinant ProteinsRhinitisSuppositoriesTreatment Outcome

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial

Language

rus

PubMed ID

18318133

Citation

Kolobukhina, L V., et al. "[Evaluation of the Efficacy of Wiferon and Arbidol in Adult Influenza]." Voprosy Virusologii, vol. 53, no. 1, 2008, pp. 31-3.
Kolobukhina LV, Malinovskaia VV, Gatich RZ, et al. [Evaluation of the efficacy of wiferon and arbidol in adult influenza]. Vopr Virusol. 2008;53(1):31-3.
Kolobukhina, L. V., Malinovskaia, V. V., Gatich, R. Z., Merkulova, L. N., Burtseva, E. I., Isaeva, E. I., Parshina, O. V., Guseva, T. S., Orlova, T. G., & Voronina, F. V. (2008). [Evaluation of the efficacy of wiferon and arbidol in adult influenza]. Voprosy Virusologii, 53(1), 31-3.
Kolobukhina LV, et al. [Evaluation of the Efficacy of Wiferon and Arbidol in Adult Influenza]. Vopr Virusol. 2008 Jan-Feb;53(1):31-3. PubMed PMID: 18318133.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Evaluation of the efficacy of wiferon and arbidol in adult influenza]. AU - Kolobukhina,L V, AU - Malinovskaia,V V, AU - Gatich,R Z, AU - Merkulova,L N, AU - Burtseva,E I, AU - Isaeva,E I, AU - Parshina,O V, AU - Guseva,T S, AU - Orlova,T G, AU - Voronina,F V, PY - 2008/3/6/pubmed PY - 2008/6/24/medline PY - 2008/3/6/entrez SP - 31 EP - 3 JF - Voprosy virusologii JO - Vopr Virusol VL - 53 IS - 1 N2 - The therapeutic efficacy of wiferon (recombinant alpha2beta-interferon) versus arbidol was studied in a double-blind controlled study in patients with laboratorily verified influenza. Within the first 24-36 hours after the onset of the disease, wiferon and arbidol reduced the duration of fever, intoxication, and the catarrhal symptoms of the disease as a whole. The agents were shown to have an immunomodulating effect. SN - 0507-4088 UR - https://www.unboundmedicine.com/medline/citation/18318133/[Evaluation_of_the_efficacy_of_wiferon_and_arbidol_in_adult_influenza]_ DB - PRIME DP - Unbound Medicine ER -