Tags

Type your tag names separated by a space and hit enter

A prospective study of waist circumference and body mass index in relation to colorectal cancer incidence.
Cancer Causes Control. 2008 Sep; 19(7):783-92.CC

Abstract

OBJECTIVES

To study the association between waist circumference and colorectal cancer, and whether it is independent of body mass index (BMI).

METHODS

Between 1997 and 2005, 953 incident colorectal cancer cases (546 men and 407 women) were identified among 95,151 participants (44,068 men and 51,083 women) from the Cancer Prevention Study-II Nutrition Cohort.

RESULTS

Waist circumference was associated with increased colorectal cancer incidence in both men (multivariable adjusted rate ratio (RR) 1.68, 95% confidence interval (CI) 1.12-2.53 for waist circumference > or =120 cm compared to <95 cm, p trend = 0.006) and women (RR 1.75, 95% CI 1.20-2.54 for > or =110 compared to <85 cm, p trend = 0.003). High levels of BMI were also associated with increased risk. After adjustment for BMI, waist circumference remained associated with a nonstatistically significant increase in colorectal cancer incidence in both men (RR 1.41, 95% CI 0.81-2.45 for > or =120 compared to <95 cm, p trend = 0.10) and women (RR 1.48, 95% CI 0.89-2.48 for > or =110 compared to <85 cm, p trend = 0.13).

CONCLUSIONS

Our results confirm that waist circumference is associated with increased colorectal cancer incidence, possibly partially independent of BMI.

Authors+Show Affiliations

Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, GA 30303-1002, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18322811

Citation

Wang, Yiting, et al. "A Prospective Study of Waist Circumference and Body Mass Index in Relation to Colorectal Cancer Incidence." Cancer Causes & Control : CCC, vol. 19, no. 7, 2008, pp. 783-92.
Wang Y, Jacobs EJ, Patel AV, et al. A prospective study of waist circumference and body mass index in relation to colorectal cancer incidence. Cancer Causes Control. 2008;19(7):783-92.
Wang, Y., Jacobs, E. J., Patel, A. V., Rodríguez, C., McCullough, M. L., Thun, M. J., & Calle, E. E. (2008). A prospective study of waist circumference and body mass index in relation to colorectal cancer incidence. Cancer Causes & Control : CCC, 19(7), 783-92. https://doi.org/10.1007/s10552-008-9141-x
Wang Y, et al. A Prospective Study of Waist Circumference and Body Mass Index in Relation to Colorectal Cancer Incidence. Cancer Causes Control. 2008;19(7):783-92. PubMed PMID: 18322811.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A prospective study of waist circumference and body mass index in relation to colorectal cancer incidence. AU - Wang,Yiting, AU - Jacobs,Eric J, AU - Patel,Alpa V, AU - Rodríguez,Carmen, AU - McCullough,Marjorie L, AU - Thun,Michael J, AU - Calle,Eugenia E, Y1 - 2008/03/06/ PY - 2007/10/15/received PY - 2008/02/20/accepted PY - 2008/3/7/pubmed PY - 2008/11/19/medline PY - 2008/3/7/entrez SP - 783 EP - 92 JF - Cancer causes & control : CCC JO - Cancer Causes Control VL - 19 IS - 7 N2 - OBJECTIVES: To study the association between waist circumference and colorectal cancer, and whether it is independent of body mass index (BMI). METHODS: Between 1997 and 2005, 953 incident colorectal cancer cases (546 men and 407 women) were identified among 95,151 participants (44,068 men and 51,083 women) from the Cancer Prevention Study-II Nutrition Cohort. RESULTS: Waist circumference was associated with increased colorectal cancer incidence in both men (multivariable adjusted rate ratio (RR) 1.68, 95% confidence interval (CI) 1.12-2.53 for waist circumference > or =120 cm compared to <95 cm, p trend = 0.006) and women (RR 1.75, 95% CI 1.20-2.54 for > or =110 compared to <85 cm, p trend = 0.003). High levels of BMI were also associated with increased risk. After adjustment for BMI, waist circumference remained associated with a nonstatistically significant increase in colorectal cancer incidence in both men (RR 1.41, 95% CI 0.81-2.45 for > or =120 compared to <95 cm, p trend = 0.10) and women (RR 1.48, 95% CI 0.89-2.48 for > or =110 compared to <85 cm, p trend = 0.13). CONCLUSIONS: Our results confirm that waist circumference is associated with increased colorectal cancer incidence, possibly partially independent of BMI. SN - 0957-5243 UR - https://www.unboundmedicine.com/medline/citation/18322811/A_prospective_study_of_waist_circumference_and_body_mass_index_in_relation_to_colorectal_cancer_incidence_ L2 - https://doi.org/10.1007/s10552-008-9141-x DB - PRIME DP - Unbound Medicine ER -