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Validation of the sleep related items of the Non-motor Symptoms Questionnaire for Parkinson's disease (NMSQuest).
Parkinsonism Relat Disord. 2008 Dec; 14(8):641-5.PR

Abstract

BACKGROUND

The Non-motor Symptoms Questionnaire (NMSQuest) is a recently developed questionnaire for the evaluation of non-motor symptoms in Parkinson's disease (PD) patients, which includes sleep disorders evaluation. The clinical validity of the questionnaire has not been explored.

OBJECTIVE

To assess the performance of the sleep/fatigue domain of the NMSQuest against other sleep measures.

METHODS

Seventy PD patients were instructed to wear an actigraph and to fill in a sleep log over seven consecutive days in addition to the Parkinson's Disease Sleep Scale (PDSS) and the NMSQuest.

RESULTS

PD patients who reported daytime sleepiness on NMSQuest obtained a significantly worse score on the PDSS sleepiness domain than PD patients who did not (12.0+/-4.7 vs. 14.7+/-3.4, p<0.009). Patients reporting difficulty getting to sleep or staying asleep at night, showed lower scores on PDSS sleep quality domain than those without difficulties (15.8+/-5.4 vs. 22.3+/-4.6, p<0.001). The presence of vivid dreams, acting out dreams and restlessness on NMSQuest correlated with PDSS and sleep log scores. Increased nocturnal activity was noted in subjects reporting acting out dreams. Furthermore, the number of positive answers to the sleep-fatigue questions of the NMSQuest correlated significantly with PDSS total score, sleep log total score and nocturnal activity measured by actigraphy.

CONCLUSION

NMSQuest sleep-fatigue domain identified appropriately sleep disturbances indicating its usefulness as a screening tool for sleep disorders in PD patients.

Authors+Show Affiliations

Movement Disorders Section, Raul Carrea Institute for Neurological Research, FLENI, Montañeses 2325, C1428AQK Cdad. Aut. Buenos Aires, Argentina.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Language

eng

PubMed ID

18329317

Citation

Perez Lloret, Santiago, et al. "Validation of the Sleep Related Items of the Non-motor Symptoms Questionnaire for Parkinson's Disease (NMSQuest)." Parkinsonism & Related Disorders, vol. 14, no. 8, 2008, pp. 641-5.
Perez Lloret S, Rossi M, Cardinali DP, et al. Validation of the sleep related items of the Non-motor Symptoms Questionnaire for Parkinson's disease (NMSQuest). Parkinsonism Relat Disord. 2008;14(8):641-5.
Perez Lloret, S., Rossi, M., Cardinali, D. P., & Merello, M. (2008). Validation of the sleep related items of the Non-motor Symptoms Questionnaire for Parkinson's disease (NMSQuest). Parkinsonism & Related Disorders, 14(8), 641-5. https://doi.org/10.1016/j.parkreldis.2008.01.004
Perez Lloret S, et al. Validation of the Sleep Related Items of the Non-motor Symptoms Questionnaire for Parkinson's Disease (NMSQuest). Parkinsonism Relat Disord. 2008;14(8):641-5. PubMed PMID: 18329317.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Validation of the sleep related items of the Non-motor Symptoms Questionnaire for Parkinson's disease (NMSQuest). AU - Perez Lloret,Santiago, AU - Rossi,Malco, AU - Cardinali,Daniel P, AU - Merello,Marcelo, Y1 - 2008/03/07/ PY - 2007/10/22/received PY - 2007/12/27/revised PY - 2008/01/09/accepted PY - 2008/3/11/pubmed PY - 2009/4/16/medline PY - 2008/3/11/entrez SP - 641 EP - 5 JF - Parkinsonism & related disorders JO - Parkinsonism Relat Disord VL - 14 IS - 8 N2 - BACKGROUND: The Non-motor Symptoms Questionnaire (NMSQuest) is a recently developed questionnaire for the evaluation of non-motor symptoms in Parkinson's disease (PD) patients, which includes sleep disorders evaluation. The clinical validity of the questionnaire has not been explored. OBJECTIVE: To assess the performance of the sleep/fatigue domain of the NMSQuest against other sleep measures. METHODS: Seventy PD patients were instructed to wear an actigraph and to fill in a sleep log over seven consecutive days in addition to the Parkinson's Disease Sleep Scale (PDSS) and the NMSQuest. RESULTS: PD patients who reported daytime sleepiness on NMSQuest obtained a significantly worse score on the PDSS sleepiness domain than PD patients who did not (12.0+/-4.7 vs. 14.7+/-3.4, p<0.009). Patients reporting difficulty getting to sleep or staying asleep at night, showed lower scores on PDSS sleep quality domain than those without difficulties (15.8+/-5.4 vs. 22.3+/-4.6, p<0.001). The presence of vivid dreams, acting out dreams and restlessness on NMSQuest correlated with PDSS and sleep log scores. Increased nocturnal activity was noted in subjects reporting acting out dreams. Furthermore, the number of positive answers to the sleep-fatigue questions of the NMSQuest correlated significantly with PDSS total score, sleep log total score and nocturnal activity measured by actigraphy. CONCLUSION: NMSQuest sleep-fatigue domain identified appropriately sleep disturbances indicating its usefulness as a screening tool for sleep disorders in PD patients. SN - 1353-8020 UR - https://www.unboundmedicine.com/medline/citation/18329317/Validation_of_the_sleep_related_items_of_the_Non_motor_Symptoms_Questionnaire_for_Parkinson's_disease__NMSQuest__ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1353-8020(08)00022-9 DB - PRIME DP - Unbound Medicine ER -