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Leptospirosis: clinical presentation and correlation with serovars.
J Commun Dis. 2007 Jun; 39(2):105-8.JC

Abstract

A total of 2400 patients with pyrexia of unknown origin and or suspected leptospirosis were included in this study. Dark field microscopy detected Leptospira in 690 cases, Leptospira serological Investigations proved positive in 570 out of these 690 patients. Among them 212 had the classical icteric and the other 358 had anicteric type of presentation. Notably eptospira interrogans serovar ictero haemorrhagiae infection was encountered in 212 patients. In 30 patients, who had multi organ dysfunction which included renal failure, hepatic dysfunction or meningitis was due to Leptospira interrogans Serovar cannicola. Coexsistense of leptospirosis and hepatitis B virus infection were noted in 15 patients. Antibody to Leptospira interrogans was demonstrated by Micro agglutination test (MAT) in addition to dark field microscopy positivity in these cases. Similarly HIV antibody was demonstrated in 30 of the 330 anicteric patients. 554 out of 570 cases responded to intra venous penicillin (216), and oral Doxycycline (182) and Augmentin (156), and the remaining 16 patients succumbed to death.

Authors+Show Affiliations

Dept. of Medicine, Rajah Muthiah Medical College & Hospital, Annamalai University, Annamalai Nagar.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18338689

Citation

Chidambaram, N, et al. "Leptospirosis: Clinical Presentation and Correlation With Serovars." The Journal of Communicable Diseases, vol. 39, no. 2, 2007, pp. 105-8.
Chidambaram N, Ramanathan M, Anandi V, et al. Leptospirosis: clinical presentation and correlation with serovars. J Commun Dis. 2007;39(2):105-8.
Chidambaram, N., Ramanathan, M., Anandi, V., Sasikala, S., Innocent, D. J., & Sarayu, L. (2007). Leptospirosis: clinical presentation and correlation with serovars. The Journal of Communicable Diseases, 39(2), 105-8.
Chidambaram N, et al. Leptospirosis: Clinical Presentation and Correlation With Serovars. J Commun Dis. 2007;39(2):105-8. PubMed PMID: 18338689.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Leptospirosis: clinical presentation and correlation with serovars. AU - Chidambaram,N, AU - Ramanathan,M, AU - Anandi,V, AU - Sasikala,S, AU - Innocent,D J P, AU - Sarayu,L, PY - 2008/3/15/pubmed PY - 2008/4/9/medline PY - 2008/3/15/entrez SP - 105 EP - 8 JF - The Journal of communicable diseases JO - J Commun Dis VL - 39 IS - 2 N2 - A total of 2400 patients with pyrexia of unknown origin and or suspected leptospirosis were included in this study. Dark field microscopy detected Leptospira in 690 cases, Leptospira serological Investigations proved positive in 570 out of these 690 patients. Among them 212 had the classical icteric and the other 358 had anicteric type of presentation. Notably eptospira interrogans serovar ictero haemorrhagiae infection was encountered in 212 patients. In 30 patients, who had multi organ dysfunction which included renal failure, hepatic dysfunction or meningitis was due to Leptospira interrogans Serovar cannicola. Coexsistense of leptospirosis and hepatitis B virus infection were noted in 15 patients. Antibody to Leptospira interrogans was demonstrated by Micro agglutination test (MAT) in addition to dark field microscopy positivity in these cases. Similarly HIV antibody was demonstrated in 30 of the 330 anicteric patients. 554 out of 570 cases responded to intra venous penicillin (216), and oral Doxycycline (182) and Augmentin (156), and the remaining 16 patients succumbed to death. SN - 0019-5138 UR - https://www.unboundmedicine.com/medline/citation/18338689/Leptospirosis:_clinical_presentation_and_correlation_with_serovars_ L2 - http://www.diseaseinfosearch.org/result/4178 DB - PRIME DP - Unbound Medicine ER -