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Factors influencing risk of macrosomia in women with gestational diabetes mellitus undergoing intensive diabetic care.
Diabetes Res Clin Pract. 2008 Jun; 80(3):405-10.DR

Abstract

AIMS

The aim of study was to assess the impact of intensive diabetic care, defined as target values for fasting glucose of 60-90mg/dl and 1-h postprandial glucose of below 130mg/dl, on neonatal birth weight in relation to risk indicators for fetal macrosomia in women with gestational diabetes mellitus (GDM).

METHODS

In women with (N=543) and without GDM (N=1011) age, height, weight, previous GDM, history of macrosomia, family history of type 2 diabetes, parity and weight gain during pregnancy were recorded.

RESULTS

Neonatal birth weight and frequency distribution of macrosomia and infants with small for gestational age did not differ between women with and without GDM. Neonatal birth weight was strongly associated with traditional risk predictors for GDM, such like prior macrosomia (OR 5.03; 95%CI 3.36-7.53), prior GDM (OR 2.52; 95%CI 1.37-4.64) and prepregnancy body mass index (BMI)>23kg/m(2) (OR 1.82; 95%CI 1.27-2.63).

CONCLUSIONS

Neonatal birth weight and the incidence of macrosomia were similar in comparison of pregnancies with and without GDM. In the population of Caucasian women the strongest single predictors for macrosomia were prior macrosomia, BMI>23kg/m(2) and prior GDM.

Authors+Show Affiliations

Department of Endocrinology, Metabolic Diseases and Internal Diseases, Pomeranian Medical University, Ul. Arkońska 4, 71-455 Szczecin, Poland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18342386

Citation

Ogonowski, Jarosław, et al. "Factors Influencing Risk of Macrosomia in Women With Gestational Diabetes Mellitus Undergoing Intensive Diabetic Care." Diabetes Research and Clinical Practice, vol. 80, no. 3, 2008, pp. 405-10.
Ogonowski J, Miazgowski T, Czeszyńska MB, et al. Factors influencing risk of macrosomia in women with gestational diabetes mellitus undergoing intensive diabetic care. Diabetes Res Clin Pract. 2008;80(3):405-10.
Ogonowski, J., Miazgowski, T., Czeszyńska, M. B., Jaskot, B., Kuczyńska, M., & Celewicz, Z. (2008). Factors influencing risk of macrosomia in women with gestational diabetes mellitus undergoing intensive diabetic care. Diabetes Research and Clinical Practice, 80(3), 405-10. https://doi.org/10.1016/j.diabres.2008.01.017
Ogonowski J, et al. Factors Influencing Risk of Macrosomia in Women With Gestational Diabetes Mellitus Undergoing Intensive Diabetic Care. Diabetes Res Clin Pract. 2008;80(3):405-10. PubMed PMID: 18342386.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors influencing risk of macrosomia in women with gestational diabetes mellitus undergoing intensive diabetic care. AU - Ogonowski,Jarosław, AU - Miazgowski,Tomasz, AU - Czeszyńska,Maria B, AU - Jaskot,Brygida, AU - Kuczyńska,Magdalena, AU - Celewicz,Zbigniew, Y1 - 2008/03/14/ PY - 2007/10/30/received PY - 2008/01/25/accepted PY - 2008/3/18/pubmed PY - 2008/8/7/medline PY - 2008/3/18/entrez SP - 405 EP - 10 JF - Diabetes research and clinical practice JO - Diabetes Res. Clin. Pract. VL - 80 IS - 3 N2 - AIMS: The aim of study was to assess the impact of intensive diabetic care, defined as target values for fasting glucose of 60-90mg/dl and 1-h postprandial glucose of below 130mg/dl, on neonatal birth weight in relation to risk indicators for fetal macrosomia in women with gestational diabetes mellitus (GDM). METHODS: In women with (N=543) and without GDM (N=1011) age, height, weight, previous GDM, history of macrosomia, family history of type 2 diabetes, parity and weight gain during pregnancy were recorded. RESULTS: Neonatal birth weight and frequency distribution of macrosomia and infants with small for gestational age did not differ between women with and without GDM. Neonatal birth weight was strongly associated with traditional risk predictors for GDM, such like prior macrosomia (OR 5.03; 95%CI 3.36-7.53), prior GDM (OR 2.52; 95%CI 1.37-4.64) and prepregnancy body mass index (BMI)>23kg/m(2) (OR 1.82; 95%CI 1.27-2.63). CONCLUSIONS: Neonatal birth weight and the incidence of macrosomia were similar in comparison of pregnancies with and without GDM. In the population of Caucasian women the strongest single predictors for macrosomia were prior macrosomia, BMI>23kg/m(2) and prior GDM. SN - 1872-8227 UR - https://www.unboundmedicine.com/medline/citation/18342386/Factors_influencing_risk_of_macrosomia_in_women_with_gestational_diabetes_mellitus_undergoing_intensive_diabetic_care_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0168-8227(08)00046-6 DB - PRIME DP - Unbound Medicine ER -