Tags

Type your tag names separated by a space and hit enter

An evaluation of the cross-protection afforded by inactivated infectious coryza vaccines.

Abstract

The cross-protection afforded by three inactivated infectious coryza vaccines was evaluated. Each vaccine contained one of the following strains of Haemophilus paragallinarum, HP31, HP60 and HP14. Strain HP31 belongs to Kume serovar C-2, strain HP60 belongs to Kume serovar C-4 while strain HP14 belongs to Kume serovar A-4. Four groups of twenty six-week-old specific-pathogen-free chickens were either given a single dose of an aluminium-hydroxide based vaccine (three groups) or left as unvaccinated controls. Three weeks after vaccination, all four groups were challenged with virulent H paragallinarum. One half of each group was challenged with the strain HP31 and the other half with strain HP60. The efficacy of the vaccines was assessed in terms of the prevention of the typical clinical signs and macroscopic lesions of infectious coryza as well as the prevention of any colonisation by the challenge organism. The serovar C-2 and serovar C-4 vaccines protected more than 50% of birds against either a serovar C-2 or C-4 challenge while the serovar A-4 vaccine protected less than 50% of birds.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    Department of Primary Industries, Animal Research Institute, Yeerongpilly, Queensland.

    Source

    Australian veterinary journal 68:8 1991 Aug pg 266-7

    MeSH

    Animals
    Bacterial Vaccines
    Chickens
    Haemophilus
    Haemophilus Infections
    Poultry Diseases
    Respiratory Tract Infections
    Specific Pathogen-Free Organisms
    Vaccination
    Vaccines, Inactivated

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    1835373

    Citation

    Blackall, P J.. "An Evaluation of the Cross-protection Afforded By Inactivated Infectious Coryza Vaccines." Australian Veterinary Journal, vol. 68, no. 8, 1991, pp. 266-7.
    Blackall PJ. An evaluation of the cross-protection afforded by inactivated infectious coryza vaccines. Aust Vet J. 1991;68(8):266-7.
    Blackall, P. J. (1991). An evaluation of the cross-protection afforded by inactivated infectious coryza vaccines. Australian Veterinary Journal, 68(8), pp. 266-7.
    Blackall PJ. An Evaluation of the Cross-protection Afforded By Inactivated Infectious Coryza Vaccines. Aust Vet J. 1991;68(8):266-7. PubMed PMID: 1835373.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - An evaluation of the cross-protection afforded by inactivated infectious coryza vaccines. A1 - Blackall,P J, PY - 1991/8/1/pubmed PY - 1991/8/1/medline PY - 1991/8/1/entrez SP - 266 EP - 7 JF - Australian veterinary journal JO - Aust. Vet. J. VL - 68 IS - 8 N2 - The cross-protection afforded by three inactivated infectious coryza vaccines was evaluated. Each vaccine contained one of the following strains of Haemophilus paragallinarum, HP31, HP60 and HP14. Strain HP31 belongs to Kume serovar C-2, strain HP60 belongs to Kume serovar C-4 while strain HP14 belongs to Kume serovar A-4. Four groups of twenty six-week-old specific-pathogen-free chickens were either given a single dose of an aluminium-hydroxide based vaccine (three groups) or left as unvaccinated controls. Three weeks after vaccination, all four groups were challenged with virulent H paragallinarum. One half of each group was challenged with the strain HP31 and the other half with strain HP60. The efficacy of the vaccines was assessed in terms of the prevention of the typical clinical signs and macroscopic lesions of infectious coryza as well as the prevention of any colonisation by the challenge organism. The serovar C-2 and serovar C-4 vaccines protected more than 50% of birds against either a serovar C-2 or C-4 challenge while the serovar A-4 vaccine protected less than 50% of birds. SN - 0005-0423 UR - https://www.unboundmedicine.com/medline/citation/1835373/An_evaluation_of_the_cross_protection_afforded_by_inactivated_infectious_coryza_vaccines_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0005-0423&date=1991&volume=68&issue=8&spage=266 DB - PRIME DP - Unbound Medicine ER -