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Needle tract seeding after vacuum-assisted breast biopsy.
Acta Radiol. 2008 Apr; 49(3):267-70.AR

Abstract

BACKGROUND

A matter of substantial concern regarding all needle biopsy techniques is seeding along the biopsy needle tract.

PURPOSE

To assess cell seeding along the needle tract of vacuum-assisted breast biopsy (VABB).

MATERIAL AND METHODS

The study included 21 patients with ductal carcinoma in situ (DCIS) and 10 patients with invasive ductal carcinoma (IDC) diagnosed by VABB for nonpalpable mammographic lesions. VABB (11G, on a Fischer table) was performed, and the duration of the procedure was measured. After surgery, the whole needle tract was embedded in paraffin blocks, stained with hematoxylin-eosin, and examined by a pathologist.

RESULTS

Cases with dissemination of cancer cells in the needle tract were not observed (one-sided 97.5% CI 0-10.0%). In 2/31 (6.5%) cases (95% CI 0.8-21.4%), benign epithelial cell displacement was observed, and the duration of VABB was significantly longer in these two cases (52.5+/-3.5 min vs. 42.0+/-4.4 min for cases without benign cell displacement; P = 0.018, Mann-Whitney-Wilcoxon test for independent samples).

CONCLUSION

No displacement of malignant cells within the 11G needle tract was documented. Benign cell displacement was associated with longer VABB duration. The phenomenon of tumor cell dissemination along the needle tract is of questionable clinical significance when the treatment guidelines are followed.

Authors+Show Affiliations

Breast Unit, First Department of Propaedeutic Surgery, Hippokratio Hospital, School of Medicine, University of Athens, Athens, Greece.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

18365811

Citation

Michalopoulos, N V., et al. "Needle Tract Seeding After Vacuum-assisted Breast Biopsy." Acta Radiologica (Stockholm, Sweden : 1987), vol. 49, no. 3, 2008, pp. 267-70.
Michalopoulos NV, Zagouri F, Sergentanis TN, et al. Needle tract seeding after vacuum-assisted breast biopsy. Acta Radiol. 2008;49(3):267-70.
Michalopoulos, N. V., Zagouri, F., Sergentanis, T. N., Pararas, N., Koulocheri, D., Nonni, A., Filippakis, G. M., Chatzipantelis, P., Bramis, J., & Zografos, G. C. (2008). Needle tract seeding after vacuum-assisted breast biopsy. Acta Radiologica (Stockholm, Sweden : 1987), 49(3), 267-70. https://doi.org/10.1080/02841850701775030
Michalopoulos NV, et al. Needle Tract Seeding After Vacuum-assisted Breast Biopsy. Acta Radiol. 2008;49(3):267-70. PubMed PMID: 18365811.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Needle tract seeding after vacuum-assisted breast biopsy. AU - Michalopoulos,N V, AU - Zagouri,F, AU - Sergentanis,T N, AU - Pararas,N, AU - Koulocheri,D, AU - Nonni,A, AU - Filippakis,G M, AU - Chatzipantelis,P, AU - Bramis,J, AU - Zografos,G C, PY - 2008/3/28/pubmed PY - 2008/4/23/medline PY - 2008/3/28/entrez SP - 267 EP - 70 JF - Acta radiologica (Stockholm, Sweden : 1987) JO - Acta Radiol VL - 49 IS - 3 N2 - BACKGROUND: A matter of substantial concern regarding all needle biopsy techniques is seeding along the biopsy needle tract. PURPOSE: To assess cell seeding along the needle tract of vacuum-assisted breast biopsy (VABB). MATERIAL AND METHODS: The study included 21 patients with ductal carcinoma in situ (DCIS) and 10 patients with invasive ductal carcinoma (IDC) diagnosed by VABB for nonpalpable mammographic lesions. VABB (11G, on a Fischer table) was performed, and the duration of the procedure was measured. After surgery, the whole needle tract was embedded in paraffin blocks, stained with hematoxylin-eosin, and examined by a pathologist. RESULTS: Cases with dissemination of cancer cells in the needle tract were not observed (one-sided 97.5% CI 0-10.0%). In 2/31 (6.5%) cases (95% CI 0.8-21.4%), benign epithelial cell displacement was observed, and the duration of VABB was significantly longer in these two cases (52.5+/-3.5 min vs. 42.0+/-4.4 min for cases without benign cell displacement; P = 0.018, Mann-Whitney-Wilcoxon test for independent samples). CONCLUSION: No displacement of malignant cells within the 11G needle tract was documented. Benign cell displacement was associated with longer VABB duration. The phenomenon of tumor cell dissemination along the needle tract is of questionable clinical significance when the treatment guidelines are followed. SN - 1600-0455 UR - https://www.unboundmedicine.com/medline/citation/18365811/Needle_tract_seeding_after_vacuum_assisted_breast_biopsy_ L2 - https://journals.sagepub.com/doi/10.1080/02841850701775030?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -