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Clinical and demographic characteristics of Epstein-Barr virus-associated childhood Burkitt's lymphoma in Southeastern Brazil: epidemiological insights from an intermediate risk region.
Haematologica 2008; 93(5):780-3H

Abstract

We studied a group of 54 children with Burkitt's lymphoma from Southeastern Brazil, where epidemiological status of Burkitt's lymphoma is poorly understood. Epstein-Barr virus association showed an intermediate frequency (~60%) between endemic and sporadic subtypes. Median age was five years. Epstein-Barr virus infection was significantly associated to low age (Epstein-Barr virus(+) four years vs. Epstein-Barr virus(-) eight years). Sex ratio (M:F) was 2:1, with a significantly higher number of males in old age classes. Young age at diagnosis and excess of males at older ages, as well as a causal relationship between low age, epstein-barr virus and Burkitt's lymphoma risk, may characterize Burkitt's lymphoma in Brazil.

Authors+Show Affiliations

Instituto Nacional de Câncer, INCA-Bone Marrow Transplantation Centre (CEMO). Praça da Cruz Vermelha 23, 6th floor, 20230-130, Rio de Janeiro, RJ, Brazil. biomol@inca.gov.brNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18367488

Citation

Hassan, Rocio, et al. "Clinical and Demographic Characteristics of Epstein-Barr Virus-associated Childhood Burkitt's Lymphoma in Southeastern Brazil: Epidemiological Insights From an Intermediate Risk Region." Haematologica, vol. 93, no. 5, 2008, pp. 780-3.
Hassan R, Klumb CE, Felisbino FE, et al. Clinical and demographic characteristics of Epstein-Barr virus-associated childhood Burkitt's lymphoma in Southeastern Brazil: epidemiological insights from an intermediate risk region. Haematologica. 2008;93(5):780-3.
Hassan, R., Klumb, C. E., Felisbino, F. E., Guiretti, D. M., White, L. R., Stefanoff, C. G., ... Zalcberg, I. R. (2008). Clinical and demographic characteristics of Epstein-Barr virus-associated childhood Burkitt's lymphoma in Southeastern Brazil: epidemiological insights from an intermediate risk region. Haematologica, 93(5), pp. 780-3. doi:10.3324/haematol.12424.
Hassan R, et al. Clinical and Demographic Characteristics of Epstein-Barr Virus-associated Childhood Burkitt's Lymphoma in Southeastern Brazil: Epidemiological Insights From an Intermediate Risk Region. Haematologica. 2008;93(5):780-3. PubMed PMID: 18367488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical and demographic characteristics of Epstein-Barr virus-associated childhood Burkitt's lymphoma in Southeastern Brazil: epidemiological insights from an intermediate risk region. AU - Hassan,Rocio, AU - Klumb,Claudete Esteves, AU - Felisbino,Fabricio E, AU - Guiretti,Deisy M, AU - White,Lídia R, AU - Stefanoff,Claudio Gustavo, AU - Barros,Mario Henrique M, AU - Seuánez,Héctor N, AU - Zalcberg,Ilana R, Y1 - 2008/03/26/ PY - 2008/3/28/pubmed PY - 2008/9/25/medline PY - 2008/3/28/entrez SP - 780 EP - 3 JF - Haematologica JO - Haematologica VL - 93 IS - 5 N2 - We studied a group of 54 children with Burkitt's lymphoma from Southeastern Brazil, where epidemiological status of Burkitt's lymphoma is poorly understood. Epstein-Barr virus association showed an intermediate frequency (~60%) between endemic and sporadic subtypes. Median age was five years. Epstein-Barr virus infection was significantly associated to low age (Epstein-Barr virus(+) four years vs. Epstein-Barr virus(-) eight years). Sex ratio (M:F) was 2:1, with a significantly higher number of males in old age classes. Young age at diagnosis and excess of males at older ages, as well as a causal relationship between low age, epstein-barr virus and Burkitt's lymphoma risk, may characterize Burkitt's lymphoma in Brazil. SN - 1592-8721 UR - https://www.unboundmedicine.com/medline/citation/18367488/Clinical_and_demographic_characteristics_of_Epstein_Barr_virus_associated_childhood_Burkitt's_lymphoma_in_Southeastern_Brazil:_epidemiological_insights_from_an_intermediate_risk_region_ L2 - http://www.haematologica.org/cgi/pmidlookup?view=long&pmid=18367488 DB - PRIME DP - Unbound Medicine ER -