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Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older.

Abstract

BACKGROUND

Depression among the elderly is an important public health issue. The aims of this study were to report the prevalence of depression and to determine the impact of socio-demographic variables, functional impairment and medical diagnoses, lifestyle factors, and mild cognitive impairment on depression as part of the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe Study).

METHODS

Included in the cross-sectional survey were 3327 non-demented subjects aged 75 and over attending general practitioners (GPs) (n=138) in an urban area of Germany. The GDS-15 Geriatric Depression Scale was used to measure depression with a threshold of <6/6+. Associations with social and clinical risk factors were assessed by means of multiple logistic regression models.

RESULTS

The prevalence of depression was 9.7% (95% confidence interval 8.7-10.7). In a univariate analysis, the following variables were significantly associated with depression: female gender, increasing age, living alone, divorce, lower educational status, functional impairment, comorbid somatic disorder, mild cognitive impairment, smoking, and abstinence from alcohol. After full adjustment for confounding variables, odds ratios for depression were significantly higher only for functional impairment, smoking, and multi-domain mild cognitive impairment.

LIMITATIONS

Recruitment procedures might have led to an underestimation of current prevalence. The cross-sectional data did not allow us to analyze the temporal relationship between risk factors and depression.

CONCLUSIONS

The prevalence of depression in the elderly is high and remains high into old age. In designing prevention programs, it is important to call more attention to the impact of functional and cognitive impairment on depression.

Links

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  • Authors+Show Affiliations

    ,

    Central Institute of Mental Health, Mannheim, Germany. siegfried.weyerer@zi-mannheim.de

    , , , , , , , , , , , , ,

    Source

    Journal of affective disorders 111:2-3 2008 Dec pg 153-63

    MeSH

    Activities of Daily Living
    Age Factors
    Aged
    Aged, 80 and over
    Cognition Disorders
    Comorbidity
    Cross-Sectional Studies
    Dementia
    Depressive Disorder
    Family Practice
    Female
    Geriatric Assessment
    Germany
    Humans
    Life Style
    Logistic Models
    Male
    Neuropsychological Tests
    Prevalence
    Primary Health Care
    Psychiatric Status Rating Scales
    Risk Factors
    Sex Factors
    Smoking

    Pub Type(s)

    Comparative Study
    Journal Article
    Multicenter Study
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    18372049

    Citation

    Weyerer, Siegfried, et al. "Prevalence and Risk Factors for Depression in Non-demented Primary Care Attenders Aged 75 Years and Older." Journal of Affective Disorders, vol. 111, no. 2-3, 2008, pp. 153-63.
    Weyerer S, Eifflaender-Gorfer S, Köhler L, et al. Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older. J Affect Disord. 2008;111(2-3):153-63.
    Weyerer, S., Eifflaender-Gorfer, S., Köhler, L., Jessen, F., Maier, W., Fuchs, A., ... Bickel, H. (2008). Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older. Journal of Affective Disorders, 111(2-3), pp. 153-63. doi:10.1016/j.jad.2008.02.008.
    Weyerer S, et al. Prevalence and Risk Factors for Depression in Non-demented Primary Care Attenders Aged 75 Years and Older. J Affect Disord. 2008;111(2-3):153-63. PubMed PMID: 18372049.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Prevalence and risk factors for depression in non-demented primary care attenders aged 75 years and older. AU - Weyerer,Siegfried, AU - Eifflaender-Gorfer,Sandra, AU - Köhler,Leonore, AU - Jessen,Frank, AU - Maier,Wolfgang, AU - Fuchs,Angela, AU - Pentzek,Michael, AU - Kaduszkiewicz,Hanna, AU - Bachmann,Cadja, AU - Angermeyer,Matthias C, AU - Luppa,Melanie, AU - Wiese,Birgitt, AU - Mösch,Edelgard, AU - Bickel,Horst, AU - ,, Y1 - 2008/03/26/ PY - 2007/12/12/received PY - 2008/02/12/revised PY - 2008/02/12/accepted PY - 2008/3/29/pubmed PY - 2009/1/24/medline PY - 2008/3/29/entrez SP - 153 EP - 63 JF - Journal of affective disorders JO - J Affect Disord VL - 111 IS - 2-3 N2 - BACKGROUND: Depression among the elderly is an important public health issue. The aims of this study were to report the prevalence of depression and to determine the impact of socio-demographic variables, functional impairment and medical diagnoses, lifestyle factors, and mild cognitive impairment on depression as part of the German Study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe Study). METHODS: Included in the cross-sectional survey were 3327 non-demented subjects aged 75 and over attending general practitioners (GPs) (n=138) in an urban area of Germany. The GDS-15 Geriatric Depression Scale was used to measure depression with a threshold of <6/6+. Associations with social and clinical risk factors were assessed by means of multiple logistic regression models. RESULTS: The prevalence of depression was 9.7% (95% confidence interval 8.7-10.7). In a univariate analysis, the following variables were significantly associated with depression: female gender, increasing age, living alone, divorce, lower educational status, functional impairment, comorbid somatic disorder, mild cognitive impairment, smoking, and abstinence from alcohol. After full adjustment for confounding variables, odds ratios for depression were significantly higher only for functional impairment, smoking, and multi-domain mild cognitive impairment. LIMITATIONS: Recruitment procedures might have led to an underestimation of current prevalence. The cross-sectional data did not allow us to analyze the temporal relationship between risk factors and depression. CONCLUSIONS: The prevalence of depression in the elderly is high and remains high into old age. In designing prevention programs, it is important to call more attention to the impact of functional and cognitive impairment on depression. SN - 0165-0327 UR - https://www.unboundmedicine.com/medline/citation/18372049/Prevalence_and_risk_factors_for_depression_in_non_demented_primary_care_attenders_aged_75_years_and_older_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0165-0327(08)00092-X DB - PRIME DP - Unbound Medicine ER -