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Sulpha allergy in lupus patients: a clinical perspective.
Lupus 2008; 17(3):202-5L

Abstract

Systemic lupus erythematosus is a chronic, relapsing autoimmune disease that can affect multiple organ systems. An increased prevalence of drug allergy has been reported in lupus patients compared with the general population. Using a cohort of 417 lupus patients, we found a history of sulpha allergy in 27.3% of patients. European-American lupus patients with sulpha allergy are about two times more likely to suffer from lymphopenia, two times more likely to have anti-Ro autoantibody, and four times less likely to have anti-nRNP antibodies compared with lupus patients without a reported sulpha allergy (P = 0.0075, 0.025, and 0.032, respectively). In African-American lupus patients, a history of sulpha allergy was associated with over three times increased odds of developing pericarditis (P = 0.005).

Authors+Show Affiliations

College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

18372360

Citation

Jeffries, M, et al. "Sulpha Allergy in Lupus Patients: a Clinical Perspective." Lupus, vol. 17, no. 3, 2008, pp. 202-5.
Jeffries M, Bruner G, Glenn S, et al. Sulpha allergy in lupus patients: a clinical perspective. Lupus. 2008;17(3):202-5.
Jeffries, M., Bruner, G., Glenn, S., Sadanandan, P., Carson, C. W., Harley, J. B., & Sawalha, A. H. (2008). Sulpha allergy in lupus patients: a clinical perspective. Lupus, 17(3), pp. 202-5. doi:10.1177/0961203307086640.
Jeffries M, et al. Sulpha Allergy in Lupus Patients: a Clinical Perspective. Lupus. 2008;17(3):202-5. PubMed PMID: 18372360.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Sulpha allergy in lupus patients: a clinical perspective. AU - Jeffries,M, AU - Bruner,G, AU - Glenn,S, AU - Sadanandan,P, AU - Carson,C W, AU - Harley,J B, AU - Sawalha,A H, PY - 2008/3/29/pubmed PY - 2008/8/13/medline PY - 2008/3/29/entrez SP - 202 EP - 5 JF - Lupus JO - Lupus VL - 17 IS - 3 N2 - Systemic lupus erythematosus is a chronic, relapsing autoimmune disease that can affect multiple organ systems. An increased prevalence of drug allergy has been reported in lupus patients compared with the general population. Using a cohort of 417 lupus patients, we found a history of sulpha allergy in 27.3% of patients. European-American lupus patients with sulpha allergy are about two times more likely to suffer from lymphopenia, two times more likely to have anti-Ro autoantibody, and four times less likely to have anti-nRNP antibodies compared with lupus patients without a reported sulpha allergy (P = 0.0075, 0.025, and 0.032, respectively). In African-American lupus patients, a history of sulpha allergy was associated with over three times increased odds of developing pericarditis (P = 0.005). SN - 0961-2033 UR - https://www.unboundmedicine.com/medline/citation/18372360/full_citation L2 - http://journals.sagepub.com/doi/full/10.1177/0961203307086640?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -