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[Second pregnancies in HIV-1-infected women. A prospective monocentric study].
Gynecol Obstet Fertil. 2008 Apr; 36(4):379-85.GO

Abstract

OBJECTIVES

To evaluate the influence of successive pregnancies on the materno-foetal prognosis in a population of HIV-infected women. Clinical, biological data and treatment strategies were compared during iterative pregnancies.

PATIENTS AND METHODS

We conducted a monocentric prospective study between August 1995 and January 2007 in a French university hospital (Nice).

RESULTS

Twenty-six HIV-infected women had two consecutive pregnancies during our study. We noticed an increase in CD4 cell count between the two pregnancies. Viral load variations were non significant. The maternal's prophylaxis changed. Percentage of HAART increased from 26 to 54%. Modes of delivery, HIV or treatments side-effects remained the same between the successive pregnancies.

DISCUSSION AND CONCLUSION

Successive pregnancies do not seem to influence the materno-foetal prognosis related to HIV infection.

Authors+Show Affiliations

Service de pédiatrie, hôpital de l'Archet-2, 151, route de Saint-Antoine-de-Ginestière, B.P. 3079, 06202 Nice cedex 3, France. monpoux.f@chu-nic.frNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

18375168

Citation

Monpoux, F, et al. "[Second Pregnancies in HIV-1-infected Women. a Prospective Monocentric Study]." Gynecologie, Obstetrique & Fertilite, vol. 36, no. 4, 2008, pp. 379-85.
Monpoux F, Delotte J, Galiba E, et al. [Second pregnancies in HIV-1-infected women. A prospective monocentric study]. Gynecol Obstet Fertil. 2008;36(4):379-85.
Monpoux, F., Delotte, J., Galiba, E., de Smet, S., Durant, J., Boutté, P., & Bongain, A. (2008). [Second pregnancies in HIV-1-infected women. A prospective monocentric study]. Gynecologie, Obstetrique & Fertilite, 36(4), 379-85. https://doi.org/10.1016/j.gyobfe.2007.11.024
Monpoux F, et al. [Second Pregnancies in HIV-1-infected Women. a Prospective Monocentric Study]. Gynecol Obstet Fertil. 2008;36(4):379-85. PubMed PMID: 18375168.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Second pregnancies in HIV-1-infected women. A prospective monocentric study]. AU - Monpoux,F, AU - Delotte,J, AU - Galiba,E, AU - de Smet,S, AU - Durant,J, AU - Boutté,P, AU - Bongain,A, Y1 - 2008/03/28/ PY - 2007/05/12/received PY - 2007/11/25/accepted PY - 2008/4/1/pubmed PY - 2008/8/6/medline PY - 2008/4/1/entrez SP - 379 EP - 85 JF - Gynecologie, obstetrique & fertilite JO - Gynecol Obstet Fertil VL - 36 IS - 4 N2 - OBJECTIVES: To evaluate the influence of successive pregnancies on the materno-foetal prognosis in a population of HIV-infected women. Clinical, biological data and treatment strategies were compared during iterative pregnancies. PATIENTS AND METHODS: We conducted a monocentric prospective study between August 1995 and January 2007 in a French university hospital (Nice). RESULTS: Twenty-six HIV-infected women had two consecutive pregnancies during our study. We noticed an increase in CD4 cell count between the two pregnancies. Viral load variations were non significant. The maternal's prophylaxis changed. Percentage of HAART increased from 26 to 54%. Modes of delivery, HIV or treatments side-effects remained the same between the successive pregnancies. DISCUSSION AND CONCLUSION: Successive pregnancies do not seem to influence the materno-foetal prognosis related to HIV infection. SN - 1297-9589 UR - https://www.unboundmedicine.com/medline/citation/18375168/[Second_pregnancies_in_HIV_1_infected_women__A_prospective_monocentric_study]_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1297-9589(08)00058-1 DB - PRIME DP - Unbound Medicine ER -