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Filarial infections in travelers and immigrants.
Curr Infect Dis Rep. 2008 Mar; 10(1):50-7.CI

Abstract

Filarial infections including loiasis, onchocerciasis, and lymphatic filariasis are important causes of morbidity in endemic populations worldwide, and they present a risk to travelers to endemic areas. Definitive diagnosis is complicated by overlap in the geographic distribution and clinical manifestations of the different filarial parasites, as well as similarities in their antigenic and nucleic acid composition. This has important implications for treatment, because the efficacies and toxicities of available antifilarial agents differ dramatically among filarial species. Recent advances, including the visualization of adult filarial worms in vivo by high-frequency ultrasound and the identification of the bacterial endosymbiont, Wolbachia, have greatly improved our understanding of the pathogenesis of filarial infection and have led to novel approaches to the diagnosis and treatment of travelers and immigrants from filarial-endemic regions.

Authors+Show Affiliations

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Building 4, Room 126, 4 Center Drive, Bethesda, MD 20892, USA. aklion@niaid.nih.gov

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18377816

Citation

Klion, Amy D.. "Filarial Infections in Travelers and Immigrants." Current Infectious Disease Reports, vol. 10, no. 1, 2008, pp. 50-7.
Klion AD. Filarial infections in travelers and immigrants. Curr Infect Dis Rep. 2008;10(1):50-7.
Klion, A. D. (2008). Filarial infections in travelers and immigrants. Current Infectious Disease Reports, 10(1), 50-7.
Klion AD. Filarial Infections in Travelers and Immigrants. Curr Infect Dis Rep. 2008;10(1):50-7. PubMed PMID: 18377816.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Filarial infections in travelers and immigrants. A1 - Klion,Amy D, PY - 2008/4/2/pubmed PY - 2008/4/2/medline PY - 2008/4/2/entrez SP - 50 EP - 7 JF - Current infectious disease reports JO - Curr Infect Dis Rep VL - 10 IS - 1 N2 - Filarial infections including loiasis, onchocerciasis, and lymphatic filariasis are important causes of morbidity in endemic populations worldwide, and they present a risk to travelers to endemic areas. Definitive diagnosis is complicated by overlap in the geographic distribution and clinical manifestations of the different filarial parasites, as well as similarities in their antigenic and nucleic acid composition. This has important implications for treatment, because the efficacies and toxicities of available antifilarial agents differ dramatically among filarial species. Recent advances, including the visualization of adult filarial worms in vivo by high-frequency ultrasound and the identification of the bacterial endosymbiont, Wolbachia, have greatly improved our understanding of the pathogenesis of filarial infection and have led to novel approaches to the diagnosis and treatment of travelers and immigrants from filarial-endemic regions. SN - 1523-3847 UR - https://www.unboundmedicine.com/medline/citation/18377816/full_citation L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=18377816.ui DB - PRIME DP - Unbound Medicine ER -
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