Tags

Type your tag names separated by a space and hit enter

Supercritical fluid extraction of cynaropicrin and 20-hydroxyecdysone from Leuzea carthamoides DC.
J Sep Sci. 2008 May; 31(8):1387-92.JS

Abstract

Leuzea carthamoides is an adaptogenic plant containing biologically active compounds as ecdysteroids and guaianolide-type sesquiterpene lactones, conventionally extracted from the plant with ethanol. It may be a potential source of the mentioned natural compounds. Ethanol-modified near-critical CO(2) was used as selective solvent with the aim to increase the level of 20-hydroxyecdysone in the extract from L. carthamoides roots and to remove selectively cynaropicrin, a sesquiterpene lactone of bitter taste, from the leaves. The extraction conditions were varied (pressure 20-28 MPa, temperature 40-60 degrees C, ethanol concentration in the solvent 0-7.1%) and the extraction yield and extract composition were compared with the results of ethanolic extraction. The supercritical fluid extraction (SFE) from finely powdered plant was controlled by phase equilibrium. Cynaropicrin was quantitatively removed from the leaves where 89% of 20-hydroxyecdysone was retained. The extraction yield of 20-hydroxyecdysone from roots with ethanol-modified CO(2)was lower by 30% than with ethanol but its concentration in the extract was higher by 67%.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Sovová H
Institute of Chemical Process Fundamentals, Academy ofSciences CR, Prague, Czech Republic. sovova@icpf.cas.cz
Opletal L
No affiliation info available
Sajfrtová M
No affiliation info available
Bártlová M
No affiliation info available

MeSH

Chemistry Techniques, AnalyticalChromatography, Supercritical FluidEcdysteroneEthanolLactonesLeuzeaModels, ChemicalPlant ExtractsPlant LeavesPlant RootsPressureSesquiterpenesSolventsTemperature

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18383243

Citation

Sovová, Helena, et al. "Supercritical Fluid Extraction of Cynaropicrin and 20-hydroxyecdysone From Leuzea Carthamoides DC." Journal of Separation Science, vol. 31, no. 8, 2008, pp. 1387-92.
Sovová H, Opletal L, Sajfrtová M, et al. Supercritical fluid extraction of cynaropicrin and 20-hydroxyecdysone from Leuzea carthamoides DC. J Sep Sci. 2008;31(8):1387-92.
Sovová, H., Opletal, L., Sajfrtová, M., & Bártlová, M. (2008). Supercritical fluid extraction of cynaropicrin and 20-hydroxyecdysone from Leuzea carthamoides DC. Journal of Separation Science, 31(8), 1387-92. https://doi.org/10.1002/jssc.200700496
Sovová H, et al. Supercritical Fluid Extraction of Cynaropicrin and 20-hydroxyecdysone From Leuzea Carthamoides DC. J Sep Sci. 2008;31(8):1387-92. PubMed PMID: 18383243.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Supercritical fluid extraction of cynaropicrin and 20-hydroxyecdysone from Leuzea carthamoides DC. AU - Sovová,Helena, AU - Opletal,Lubomír, AU - Sajfrtová,Marie, AU - Bártlová,Milena, PY - 2008/4/3/pubmed PY - 2008/8/22/medline PY - 2008/4/3/entrez SP - 1387 EP - 92 JF - Journal of separation science JO - J Sep Sci VL - 31 IS - 8 N2 - Leuzea carthamoides is an adaptogenic plant containing biologically active compounds as ecdysteroids and guaianolide-type sesquiterpene lactones, conventionally extracted from the plant with ethanol. It may be a potential source of the mentioned natural compounds. Ethanol-modified near-critical CO(2) was used as selective solvent with the aim to increase the level of 20-hydroxyecdysone in the extract from L. carthamoides roots and to remove selectively cynaropicrin, a sesquiterpene lactone of bitter taste, from the leaves. The extraction conditions were varied (pressure 20-28 MPa, temperature 40-60 degrees C, ethanol concentration in the solvent 0-7.1%) and the extraction yield and extract composition were compared with the results of ethanolic extraction. The supercritical fluid extraction (SFE) from finely powdered plant was controlled by phase equilibrium. Cynaropicrin was quantitatively removed from the leaves where 89% of 20-hydroxyecdysone was retained. The extraction yield of 20-hydroxyecdysone from roots with ethanol-modified CO(2)was lower by 30% than with ethanol but its concentration in the extract was higher by 67%. SN - 1615-9314 UR - https://www.unboundmedicine.com/medline/citation/18383243/Supercritical_fluid_extraction_of_cynaropicrin_and_20_hydroxyecdysone_from_Leuzea_carthamoides_DC_ DB - PRIME DP - Unbound Medicine ER -