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Patient-controlled analgesia in chronic pain patients: experience with a new device designed to be used with implanted programmable pumps.
Pain Pract. 2008 May-Jun; 8(3):164-70.PP

Abstract

BACKGROUND

Intrathecal drug delivery using implantable pumps is an effective method to control stable chronic pain. However, the appropriate alleviation of unpredictable pain fluctuations remains challenging. A possible solution is the use of patient-controlled analgesia (PCA) by means of a specific device--the personal therapy manager (PTM)--designed to be used with implanted programmable pumps.

METHODS

A multicenter (n = 17), open-label registry recording 168 patients suffering from chronic pain with unsatisfactory control of pain episodes was initiated. While 79 patients (47%) (group A) already carried an implanted pump at enrollment, all other patients were implanted after being registered in the study (group B). Parameters assessed included pain relief (visual analog score, VAS), quality of life (EQ-5D), patient and physician satisfaction, medication use, PTM programming parameters and adverse events. Final follow-up was at 12 months.

RESULTS

At 12 months, there was a significant reduction (29%) of the overall average VAS compared with baseline (P < 0.01) in patients with newly implanted devices (group B). All patients tended to decrease the concomitant pain medication and the quality of life tended to improve (10% on the EQ-5D scale). In total, 85% of patients were satisfied with the PTM. No serious adverse events related to the use of the PTM device were observed.

CONCLUSIONS

Patient-controlled analgesia using a PTM with a programmable, implantable pump system is an effective therapy for the treatment of chronic pain and allows patients to feel that they have more control over unpredictable pain fluctuations.

Authors+Show Affiliations

Krankenhaus der Barmherzigen Brueder, Wien, Austria. wilfried.ilias@bbwien.atNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18384501

Citation

Ilias, Wilfried, et al. "Patient-controlled Analgesia in Chronic Pain Patients: Experience With a New Device Designed to Be Used With Implanted Programmable Pumps." Pain Practice : the Official Journal of World Institute of Pain, vol. 8, no. 3, 2008, pp. 164-70.
Ilias W, le Polain B, Buchser E, et al. Patient-controlled analgesia in chronic pain patients: experience with a new device designed to be used with implanted programmable pumps. Pain Pract. 2008;8(3):164-70.
Ilias, W., le Polain, B., Buchser, E., & Demartini, L. (2008). Patient-controlled analgesia in chronic pain patients: experience with a new device designed to be used with implanted programmable pumps. Pain Practice : the Official Journal of World Institute of Pain, 8(3), 164-70. https://doi.org/10.1111/j.1533-2500.2008.00187.x
Ilias W, et al. Patient-controlled Analgesia in Chronic Pain Patients: Experience With a New Device Designed to Be Used With Implanted Programmable Pumps. Pain Pract. 2008 May-Jun;8(3):164-70. PubMed PMID: 18384501.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Patient-controlled analgesia in chronic pain patients: experience with a new device designed to be used with implanted programmable pumps. AU - Ilias,Wilfried, AU - le Polain,Bernard, AU - Buchser,Eric, AU - Demartini,Laura, AU - ,, Y1 - 2008/03/31/ PY - 2008/4/4/pubmed PY - 2008/6/25/medline PY - 2008/4/4/entrez SP - 164 EP - 70 JF - Pain practice : the official journal of World Institute of Pain JO - Pain Pract VL - 8 IS - 3 N2 - BACKGROUND: Intrathecal drug delivery using implantable pumps is an effective method to control stable chronic pain. However, the appropriate alleviation of unpredictable pain fluctuations remains challenging. A possible solution is the use of patient-controlled analgesia (PCA) by means of a specific device--the personal therapy manager (PTM)--designed to be used with implanted programmable pumps. METHODS: A multicenter (n = 17), open-label registry recording 168 patients suffering from chronic pain with unsatisfactory control of pain episodes was initiated. While 79 patients (47%) (group A) already carried an implanted pump at enrollment, all other patients were implanted after being registered in the study (group B). Parameters assessed included pain relief (visual analog score, VAS), quality of life (EQ-5D), patient and physician satisfaction, medication use, PTM programming parameters and adverse events. Final follow-up was at 12 months. RESULTS: At 12 months, there was a significant reduction (29%) of the overall average VAS compared with baseline (P < 0.01) in patients with newly implanted devices (group B). All patients tended to decrease the concomitant pain medication and the quality of life tended to improve (10% on the EQ-5D scale). In total, 85% of patients were satisfied with the PTM. No serious adverse events related to the use of the PTM device were observed. CONCLUSIONS: Patient-controlled analgesia using a PTM with a programmable, implantable pump system is an effective therapy for the treatment of chronic pain and allows patients to feel that they have more control over unpredictable pain fluctuations. SN - 1533-2500 UR - https://www.unboundmedicine.com/medline/citation/18384501/Patient_controlled_analgesia_in_chronic_pain_patients:_experience_with_a_new_device_designed_to_be_used_with_implanted_programmable_pumps_ DB - PRIME DP - Unbound Medicine ER -