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Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales.
J Pediatr Orthop. 2008 Mar; 28(2):213-7.JP

Abstract

BACKGROUND

The literature available shows that spasticity in patients with cerebral palsy (CP) is reduced by intrathecal baclofen (ITB) treatment, and various studies suggest that this treatment can also be used in dystonic patients. The aim of the present study was to evaluate dystonia treated with ITB in children with CP.

METHODS

Data of 19 patients affected by dystonia as an outcome of infant CP in patients belonging to level V of Gross Motor Function Classification System treated with ITB were collected. The mean age at implant is 8.49 years.The patients are assessed using Barry-Albright Scale and Burke-Fahn-Marsden Scale before treatment and at 3, 6, and 12 months postimplant.

RESULTS

The results showed a statistically significant improvement (P < 0.001) in the total scores of the 2 scales after just 3 months of treatment, an improvement that was maintained for the 1-year period of follow-up. The results also revealed a reduction in dystonias, an improvement in posture, and an easing of the task of the caregivers in managing the patient as a result of treatment with ITB.

CONCLUSIONS

In patients belonging to level V of Gross Motor Function Classification System and treated with ITB, a decrease in frequency and severity of dystonia is observed. This improvement eases caregiver in patient management.

LEVEL OF EVIDENCE

Therapeutic Level IV.

Authors+Show Affiliations

Department of Pediatric Orthopedics, V. Buzzi Children's Hospital, Via Castelvetro 32, Milan, Italy. f.motta@icp.mi.itNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18388717

Citation

Motta, Francesco, et al. "Effect of Intrathecal Baclofen On Dystonia in Children With Cerebral Palsy and the Use of Functional Scales." Journal of Pediatric Orthopedics, vol. 28, no. 2, 2008, pp. 213-7.
Motta F, Stignani C, Antonello CE. Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales. J Pediatr Orthop. 2008;28(2):213-7.
Motta, F., Stignani, C., & Antonello, C. E. (2008). Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales. Journal of Pediatric Orthopedics, 28(2), 213-7. https://doi.org/10.1097/BPO.0b013e3181653b2a
Motta F, Stignani C, Antonello CE. Effect of Intrathecal Baclofen On Dystonia in Children With Cerebral Palsy and the Use of Functional Scales. J Pediatr Orthop. 2008;28(2):213-7. PubMed PMID: 18388717.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of intrathecal baclofen on dystonia in children with cerebral palsy and the use of functional scales. AU - Motta,Francesco, AU - Stignani,Cecilia, AU - Antonello,Clara Eleonora, PY - 2008/4/5/pubmed PY - 2008/5/9/medline PY - 2008/4/5/entrez SP - 213 EP - 7 JF - Journal of pediatric orthopedics JO - J Pediatr Orthop VL - 28 IS - 2 N2 - BACKGROUND: The literature available shows that spasticity in patients with cerebral palsy (CP) is reduced by intrathecal baclofen (ITB) treatment, and various studies suggest that this treatment can also be used in dystonic patients. The aim of the present study was to evaluate dystonia treated with ITB in children with CP. METHODS: Data of 19 patients affected by dystonia as an outcome of infant CP in patients belonging to level V of Gross Motor Function Classification System treated with ITB were collected. The mean age at implant is 8.49 years.The patients are assessed using Barry-Albright Scale and Burke-Fahn-Marsden Scale before treatment and at 3, 6, and 12 months postimplant. RESULTS: The results showed a statistically significant improvement (P < 0.001) in the total scores of the 2 scales after just 3 months of treatment, an improvement that was maintained for the 1-year period of follow-up. The results also revealed a reduction in dystonias, an improvement in posture, and an easing of the task of the caregivers in managing the patient as a result of treatment with ITB. CONCLUSIONS: In patients belonging to level V of Gross Motor Function Classification System and treated with ITB, a decrease in frequency and severity of dystonia is observed. This improvement eases caregiver in patient management. LEVEL OF EVIDENCE: Therapeutic Level IV. SN - 0271-6798 UR - https://www.unboundmedicine.com/medline/citation/18388717/Effect_of_intrathecal_baclofen_on_dystonia_in_children_with_cerebral_palsy_and_the_use_of_functional_scales_ L2 - http://Insights.ovid.com/pubmed?pmid=18388717 DB - PRIME DP - Unbound Medicine ER -