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Evaluation of antioxidant and antimicrobial properties of Soymida febrifuga leaf extracts.
Phytother Res. 2008 Jul; 22(7):943-7.PR

Abstract

The present study was designed to evaluate the antioxidant and antimicrobial properties of hexane (LH), methanol (LM) and aqueous (LA) extracts of Soymida febrifuga (Maliaceae) leaves, which is a traditional folk medicine in India. No pharmacological evaluation of this plant (except antiplasmodial activity) has been reported to date. Antioxidant activity of different extracts was evaluated by DPPH free radical scavenging activity, taking total phenolic content (TPC) as an index. Antimicrobial activity was tested against six bacterial and five fungal strains using the agar hole diffusion method and the minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) were determined for all the test organisms against the extracts. The results showed that the methanol and aqueous extracts of leaf had a higher antioxidant activity and total phenolic content than the hexane extract. The antioxidant activity and TPC of the extracts were highly correlated. Extracts also showed several degrees of antimicrobial activity against different microbes. The methanol extract was more potent against Aspergillus fumigatus and Candida tropicana. The lowest MIC values obtained for LM, LA and LH were 78, 156, 625 microg/mL against A. fumigatus, C. tropicana and C. albicans, respectively. Hence, this study confirms that Soymida febrifuga leaves possess potent antioxidant and antimicrobial activity.

Authors+Show Affiliations

Pharmacology Division, Indian Institute of Chemical Technology, Uppal Road, Hyderabad 500007, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18389470

Citation

Reddy, Boreddy Srinivas, et al. "Evaluation of Antioxidant and Antimicrobial Properties of Soymida Febrifuga Leaf Extracts." Phytotherapy Research : PTR, vol. 22, no. 7, 2008, pp. 943-7.
Reddy BS, Reddy BP, Raghavulu SV, et al. Evaluation of antioxidant and antimicrobial properties of Soymida febrifuga leaf extracts. Phytother Res. 2008;22(7):943-7.
Reddy, B. S., Reddy, B. P., Raghavulu, S. V., Ramakrishna, S., Venkateswarlu, Y., & Diwan, P. V. (2008). Evaluation of antioxidant and antimicrobial properties of Soymida febrifuga leaf extracts. Phytotherapy Research : PTR, 22(7), 943-7. https://doi.org/10.1002/ptr.2433
Reddy BS, et al. Evaluation of Antioxidant and Antimicrobial Properties of Soymida Febrifuga Leaf Extracts. Phytother Res. 2008;22(7):943-7. PubMed PMID: 18389470.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation of antioxidant and antimicrobial properties of Soymida febrifuga leaf extracts. AU - Reddy,Boreddy Srinivas, AU - Reddy,Boreddy Purushotham, AU - Raghavulu,Sapireddy Veer, AU - Ramakrishna,Sistla, AU - Venkateswarlu,Y, AU - Diwan,Prakash V, PY - 2008/4/5/pubmed PY - 2008/8/8/medline PY - 2008/4/5/entrez SP - 943 EP - 7 JF - Phytotherapy research : PTR JO - Phytother Res VL - 22 IS - 7 N2 - The present study was designed to evaluate the antioxidant and antimicrobial properties of hexane (LH), methanol (LM) and aqueous (LA) extracts of Soymida febrifuga (Maliaceae) leaves, which is a traditional folk medicine in India. No pharmacological evaluation of this plant (except antiplasmodial activity) has been reported to date. Antioxidant activity of different extracts was evaluated by DPPH free radical scavenging activity, taking total phenolic content (TPC) as an index. Antimicrobial activity was tested against six bacterial and five fungal strains using the agar hole diffusion method and the minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) were determined for all the test organisms against the extracts. The results showed that the methanol and aqueous extracts of leaf had a higher antioxidant activity and total phenolic content than the hexane extract. The antioxidant activity and TPC of the extracts were highly correlated. Extracts also showed several degrees of antimicrobial activity against different microbes. The methanol extract was more potent against Aspergillus fumigatus and Candida tropicana. The lowest MIC values obtained for LM, LA and LH were 78, 156, 625 microg/mL against A. fumigatus, C. tropicana and C. albicans, respectively. Hence, this study confirms that Soymida febrifuga leaves possess potent antioxidant and antimicrobial activity. SN - 1099-1573 UR - https://www.unboundmedicine.com/medline/citation/18389470/Evaluation_of_antioxidant_and_antimicrobial_properties_of_Soymida_febrifuga_leaf_extracts_ L2 - https://doi.org/10.1002/ptr.2433 DB - PRIME DP - Unbound Medicine ER -