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Posttraumatic stress disorder, gender, and problem profiles in substance dependent patients.
Subst Use Misuse. 2008; 43(5):596-611.SU

Abstract

Patients with a chronic and severe substance-use disorder who also have a history of posttraumatic stress disorder (PTSD) are thought to have a unique set of problems. The present study assessed psychiatric disorders, psychosocial problems, and traumatic events with structured interviews in 747 men and 693 women enrolling in urban opioid substitution treatment programs from 1995 to 2001. Participants with versus without a history of PTSD were more likely to have a history of many other psychiatric disorders and demonstrated more current and historical medical, employment, family/social, and psychiatric problems. PTSD was generally unrelated to substance-use disorder severity or diagnoses, with the exception of an increased risk of alcohol dependence. Women were more likely than men to have experienced sexual assault, and less likely to have been physically assaulted, although these events precipitated PTSD at equivalent rates across gender. In contrast, witnessing or hearing about the death or injury of others was more likely to precipitate PTSD in women than men. Female gender, exposure to combat, sexual assault, or physical assault, and a history of major mood or anxiety disorder were the best predictors of PTSD in this group. Study limitations are noted.

Authors+Show Affiliations

Addiction Treatment Services, Johns Hopkins Bayview Medical Center, Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21224, USA. jmpeirce@jhmi.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, N.I.H., Extramural

Language

eng

PubMed ID

18393079

Citation

Peirce, Jessica M., et al. "Posttraumatic Stress Disorder, Gender, and Problem Profiles in Substance Dependent Patients." Substance Use & Misuse, vol. 43, no. 5, 2008, pp. 596-611.
Peirce JM, Kindbom KA, Waesche MC, et al. Posttraumatic stress disorder, gender, and problem profiles in substance dependent patients. Subst Use Misuse. 2008;43(5):596-611.
Peirce, J. M., Kindbom, K. A., Waesche, M. C., Yuscavage, A. S., & Brooner, R. K. (2008). Posttraumatic stress disorder, gender, and problem profiles in substance dependent patients. Substance Use & Misuse, 43(5), 596-611. https://doi.org/10.1080/10826080701204623
Peirce JM, et al. Posttraumatic Stress Disorder, Gender, and Problem Profiles in Substance Dependent Patients. Subst Use Misuse. 2008;43(5):596-611. PubMed PMID: 18393079.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Posttraumatic stress disorder, gender, and problem profiles in substance dependent patients. AU - Peirce,Jessica M, AU - Kindbom,Kori A, AU - Waesche,Matthew C, AU - Yuscavage,Abigail S E, AU - Brooner,Robert K, PY - 2008/4/9/pubmed PY - 2008/7/18/medline PY - 2008/4/9/entrez SP - 596 EP - 611 JF - Substance use & misuse JO - Subst Use Misuse VL - 43 IS - 5 N2 - Patients with a chronic and severe substance-use disorder who also have a history of posttraumatic stress disorder (PTSD) are thought to have a unique set of problems. The present study assessed psychiatric disorders, psychosocial problems, and traumatic events with structured interviews in 747 men and 693 women enrolling in urban opioid substitution treatment programs from 1995 to 2001. Participants with versus without a history of PTSD were more likely to have a history of many other psychiatric disorders and demonstrated more current and historical medical, employment, family/social, and psychiatric problems. PTSD was generally unrelated to substance-use disorder severity or diagnoses, with the exception of an increased risk of alcohol dependence. Women were more likely than men to have experienced sexual assault, and less likely to have been physically assaulted, although these events precipitated PTSD at equivalent rates across gender. In contrast, witnessing or hearing about the death or injury of others was more likely to precipitate PTSD in women than men. Female gender, exposure to combat, sexual assault, or physical assault, and a history of major mood or anxiety disorder were the best predictors of PTSD in this group. Study limitations are noted. SN - 1082-6084 UR - https://www.unboundmedicine.com/medline/citation/18393079/Posttraumatic_stress_disorder_gender_and_problem_profiles_in_substance_dependent_patients_ L2 - https://www.tandfonline.com/doi/full/10.1080/10826080701204623 DB - PRIME DP - Unbound Medicine ER -