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Asymmetric direct aldol reactions of pyruvic derivatives.
Org Lett. 2008 May 01; 10(9):1775-8.OL

Abstract

Simple chiral primary-tertiary diamine-Brønsted acid conjugates such as 1e can effectively catalyze the direct aldol reactions of pyruvic derivatives with excellent syn diastereoselectivities and enantioselectivities, thus functionally mimicking the pyruvate-dependent type I aldolases.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Luo S
Beijing National Laboratory for Molecular Sciences, Center for Chemical Biology, Institute of Chemistry and Graduate School, Chinese Academy of Sciences, Beijing, China. luosz@iccas.ac.cn
Xu H
No affiliation info available
Chen L
No affiliation info available
Cheng JP
No affiliation info available

MeSH

Aldehyde-LyasesAldehydesCatalysisDiaminesPyruvic AcidStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18393517

Citation

Luo, Sanzhong, et al. "Asymmetric Direct Aldol Reactions of Pyruvic Derivatives." Organic Letters, vol. 10, no. 9, 2008, pp. 1775-8.
Luo S, Xu H, Chen L, et al. Asymmetric direct aldol reactions of pyruvic derivatives. Org Lett. 2008;10(9):1775-8.
Luo, S., Xu, H., Chen, L., & Cheng, J. P. (2008). Asymmetric direct aldol reactions of pyruvic derivatives. Organic Letters, 10(9), 1775-8. https://doi.org/10.1021/ol800471b
Luo S, et al. Asymmetric Direct Aldol Reactions of Pyruvic Derivatives. Org Lett. 2008 May 1;10(9):1775-8. PubMed PMID: 18393517.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Asymmetric direct aldol reactions of pyruvic derivatives. AU - Luo,Sanzhong, AU - Xu,Hui, AU - Chen,Liujuan, AU - Cheng,Jin-Pei, Y1 - 2008/04/08/ PY - 2008/4/9/pubmed PY - 2008/8/8/medline PY - 2008/4/9/entrez SP - 1775 EP - 8 JF - Organic letters JO - Org Lett VL - 10 IS - 9 N2 - Simple chiral primary-tertiary diamine-Brønsted acid conjugates such as 1e can effectively catalyze the direct aldol reactions of pyruvic derivatives with excellent syn diastereoselectivities and enantioselectivities, thus functionally mimicking the pyruvate-dependent type I aldolases. SN - 1523-7060 UR - https://www.unboundmedicine.com/medline/citation/18393517/Asymmetric_direct_aldol_reactions_of_pyruvic_derivatives_ DB - PRIME DP - Unbound Medicine ER -