TY - JOUR T1 - Characterization of phenolic compounds in the Chinese herbal drug Artemisia annua by liquid chromatography coupled to electrospray ionization mass spectrometry. AU - Han,Jian, AU - Ye,Min, AU - Qiao,Xue, AU - Xu,Man, AU - Wang,Bao-Rong, AU - Guo,De-An, Y1 - 2008/03/10/ PY - 2007/10/26/received PY - 2008/01/31/revised PY - 2008/02/06/accepted PY - 2008/4/9/pubmed PY - 2008/9/10/medline PY - 2008/4/9/entrez SP - 516 EP - 25 JF - Journal of pharmaceutical and biomedical analysis JO - J Pharm Biomed Anal VL - 47 IS - 3 N2 - A simple and rapid method has been established for the screening of the main phenolic compounds in Artemisia annua by LC-DAD-ESI-MS(n). A total of 40 phenolic compounds were identified or tentatively characterized in the methanol extract of A. annua, including 8 C-glycosyl flavonoids, 5 O-glycosyl flavonoids, 3 flavonoid aglycones, 21 quinic acid derivatives, 2 benzoicacid glucosides and 1 coumarin. The C-glycosyl flavonoids were reported from A. annua for the first time and they were found to be a new type of main constituents, and might be responsible for its antioxidant and antiviral activity. Quinic acid derivatives were also found to be the major constituents of A. annua. SN - 0731-7085 UR - https://www.unboundmedicine.com/medline/citation/18394841/Characterization_of_phenolic_compounds_in_the_Chinese_herbal_drug_Artemisia_annua_by_liquid_chromatography_coupled_to_electrospray_ionization_mass_spectrometry_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0731-7085(08)00101-5 DB - PRIME DP - Unbound Medicine ER -