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Effects of honey as a scolicidal agent on the hepatobiliary system.

Abstract

AIM

To examine the effects of 10% diluted honey, which has been shown to be scolicidal, on the liver and biliary system and determine whether it could be used as a scolicidal agent in the presence of biliary-cystic communication.

METHODS

Thirty Wistar-Albino rats were divided into two groups. Honey with 10% dilution in the study group and 0.9% saline (NaCl) in the control group were injected into the common bile ducts of rats through a 3-mm duodenotomy. The animals were sacrificed 6 mo after the procedure. Histopathological, biochemical, and radiological examinations were performed for evaluation of side effects.

RESULTS

At the end of the sixth month, liver function tests were found to be normal in both groups. The tissue samples of liver and ductus choledochus of the honey group showed no histomorphologic difference from the control group. No stricture on the biliary tree was detected on the retrograde cholangiograms.

CONCLUSION

According to these results, we concluded that 10% diluted honey could be used as scolicidal agent safely in the presence of biliary-cystic communication.

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  • Authors+Show Affiliations

    ,

    Department of General Surgery, Ankara Training and Research Hospital, Ankara 06340, Turkey. kilicoglubulent@yahoo.com

    , , , , , , , ,

    Source

    World journal of gastroenterology 14:13 2008 Apr 07 pg 2085-8

    MeSH

    Animals
    Bile Ducts
    Common Bile Duct
    Female
    Honey
    Humans
    Liver
    Rats
    Rats, Wistar
    Salts

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    18395911

    Citation

    Kilicoglu, Bulent, et al. "Effects of Honey as a Scolicidal Agent On the Hepatobiliary System." World Journal of Gastroenterology, vol. 14, no. 13, 2008, pp. 2085-8.
    Kilicoglu B, Kismet K, Kilicoglu SS, et al. Effects of honey as a scolicidal agent on the hepatobiliary system. World J Gastroenterol. 2008;14(13):2085-8.
    Kilicoglu, B., Kismet, K., Kilicoglu, S. S., Erel, S., Gencay, O., Sorkun, K., ... Sayek, I. (2008). Effects of honey as a scolicidal agent on the hepatobiliary system. World Journal of Gastroenterology, 14(13), pp. 2085-8.
    Kilicoglu B, et al. Effects of Honey as a Scolicidal Agent On the Hepatobiliary System. World J Gastroenterol. 2008 Apr 7;14(13):2085-8. PubMed PMID: 18395911.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Effects of honey as a scolicidal agent on the hepatobiliary system. AU - Kilicoglu,Bulent, AU - Kismet,Kemal, AU - Kilicoglu,Sibel-Serin, AU - Erel,Serap, AU - Gencay,Omur, AU - Sorkun,Kadriye, AU - Erdemli,Esra, AU - Akhan,Okan, AU - Akkus,Mehmet-Ali, AU - Sayek,Iskender, PY - 2008/4/9/pubmed PY - 2008/7/29/medline PY - 2008/4/9/entrez SP - 2085 EP - 8 JF - World journal of gastroenterology JO - World J. Gastroenterol. VL - 14 IS - 13 N2 - AIM: To examine the effects of 10% diluted honey, which has been shown to be scolicidal, on the liver and biliary system and determine whether it could be used as a scolicidal agent in the presence of biliary-cystic communication. METHODS: Thirty Wistar-Albino rats were divided into two groups. Honey with 10% dilution in the study group and 0.9% saline (NaCl) in the control group were injected into the common bile ducts of rats through a 3-mm duodenotomy. The animals were sacrificed 6 mo after the procedure. Histopathological, biochemical, and radiological examinations were performed for evaluation of side effects. RESULTS: At the end of the sixth month, liver function tests were found to be normal in both groups. The tissue samples of liver and ductus choledochus of the honey group showed no histomorphologic difference from the control group. No stricture on the biliary tree was detected on the retrograde cholangiograms. CONCLUSION: According to these results, we concluded that 10% diluted honey could be used as scolicidal agent safely in the presence of biliary-cystic communication. SN - 1007-9327 UR - https://www.unboundmedicine.com/medline/citation/18395911/Effects_of_honey_as_a_scolicidal_agent_on_the_hepatobiliary_system_ L2 - http://www.wjgnet.com/1007-9327/full/v14/i13/2085.htm DB - PRIME DP - Unbound Medicine ER -