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A clinical and histopathologic study of granulomatous rosacea.
J Am Acad Dermatol. 1991 Dec; 25(6 Pt 1):1038-43.JA

Abstract

A retrospective clinical and histopathologic study of 53 patients with granulomatous rosacea was undertaken. The patients had a broad clinical spectrum of lesions that ranged from primarily erythema to papulonodular lesions. Extrafacial lesions occurred in 15% of patients. Histologic examination showed mixed lymphohistiocytic inflammation (primarily lymphocytic inflammation in 40% of patients and primarily histiocytic with a few giant cells in 34%), epithelioid granulomas in 11% of patients, and epithelioid granulomas with caseation necrosis in 11%. Most patients had a good response to oral antibiotic therapy. Granulomatous rosacea is not a distinct disease but can be regarded and treated as a subtype of rosacea.

Authors+Show Affiliations

Helm KF
Department of Dermatology, Mayo Clinic, Rochester, MN 55905.
Menz J
No affiliation info available
Gibson LE
No affiliation info available
Dicken CH
No affiliation info available

MeSH

AgedAged, 80 and overBlisterElastic TissueErythemaFemaleFolliculitisGranulomaHistiocytesHumansLymphocytesMaleMiddle AgedRetrospective StudiesRosaceaSingle-Blind MethodSkinSkin AgingTelangiectasis

Pub Type(s)

Journal Article

Language

eng

PubMed ID

1839796

Citation

Helm, K F., et al. "A Clinical and Histopathologic Study of Granulomatous Rosacea." Journal of the American Academy of Dermatology, vol. 25, no. 6 Pt 1, 1991, pp. 1038-43.
Helm KF, Menz J, Gibson LE, et al. A clinical and histopathologic study of granulomatous rosacea. J Am Acad Dermatol. 1991;25(6 Pt 1):1038-43.
Helm, K. F., Menz, J., Gibson, L. E., & Dicken, C. H. (1991). A clinical and histopathologic study of granulomatous rosacea. Journal of the American Academy of Dermatology, 25(6 Pt 1), 1038-43.
Helm KF, et al. A Clinical and Histopathologic Study of Granulomatous Rosacea. J Am Acad Dermatol. 1991;25(6 Pt 1):1038-43. PubMed PMID: 1839796.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A clinical and histopathologic study of granulomatous rosacea. AU - Helm,K F, AU - Menz,J, AU - Gibson,L E, AU - Dicken,C H, PY - 1991/12/1/pubmed PY - 1991/12/1/medline PY - 1991/12/1/entrez SP - 1038 EP - 43 JF - Journal of the American Academy of Dermatology JO - J Am Acad Dermatol VL - 25 IS - 6 Pt 1 N2 - A retrospective clinical and histopathologic study of 53 patients with granulomatous rosacea was undertaken. The patients had a broad clinical spectrum of lesions that ranged from primarily erythema to papulonodular lesions. Extrafacial lesions occurred in 15% of patients. Histologic examination showed mixed lymphohistiocytic inflammation (primarily lymphocytic inflammation in 40% of patients and primarily histiocytic with a few giant cells in 34%), epithelioid granulomas in 11% of patients, and epithelioid granulomas with caseation necrosis in 11%. Most patients had a good response to oral antibiotic therapy. Granulomatous rosacea is not a distinct disease but can be regarded and treated as a subtype of rosacea. SN - 0190-9622 UR - https://www.unboundmedicine.com/medline/citation/1839796/A_clinical_and_histopathologic_study_of_granulomatous_rosacea_ DB - PRIME DP - Unbound Medicine ER -