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[The relationship of ankle brachial index to all-cause and cardiovascular disease mortality in Chinese male patients with hypertension].
Zhonghua Yu Fang Yi Xue Za Zhi. 2007 Nov; 41(6):487-91.ZY

Abstract

OBJECTIVE

To evaluate the risk factors for peripheral arterial disease (PAD) and the relationship of low ankle brachial index (ABI) to all-cause and cardiovascular disease (CVD) mortality in Chinese male patients with hypertension.

METHODS

The data of 1606 male participants with hypertension from the eight hospitals in Beijing and Shanghai were analyzed. ABI was ascertained at baseline by measuring the systolic pressures on bilateral brachial and tibial arteries. ABI < or = 0.9 was used as the diagnostic criteria for PAD identification. The follow-up survey was conducted from November 2005 to January 2006.

RESULTS

Of 1606 male participants with hypertension at baseline, 406 (25.3%) were in low-ABI group and 1200 (74.7%) were in normal-ABI group. Older age, TC, history of diabetes, history of smoking and 2-grade hypertension were associated with low ABI in male patients with hypertension. During the (12.87 +/- 2.94) months follow-up, there were 153 deaths. Of which, 62 were attributable to CVD. Low ABI was associated with adjusted all-cause and CVD mortality risk of 1.728 (1.223-2.441) and 2.388 (1.409-4.046) respectively in Cox regression models. Rate of survival for the low-ABI group was significantly worse than for the normal-ABI group. The risk of all-cause and CVD mortality was increased with the decline of ABI.

CONCLUSION

Low ABI is independently associated with the high risks of all-cause and CVD mortality in Chinese male patients with hypertension. The utility of ABI as a tool for predicting mortality in the patients with hypertension should be popularized.

Authors+Show Affiliations

Center for Cardiovascular and Pulmonary Blood Vessel, Tongji University, Shanghai 200092, ChinaNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

18399131

Citation

Guo, Wei-Wei, et al. "[The Relationship of Ankle Brachial Index to All-cause and Cardiovascular Disease Mortality in Chinese Male Patients With Hypertension]." Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine], vol. 41, no. 6, 2007, pp. 487-91.
Guo WW, Li J, Yu JM, et al. [The relationship of ankle brachial index to all-cause and cardiovascular disease mortality in Chinese male patients with hypertension]. Zhonghua Yu Fang Yi Xue Za Zhi. 2007;41(6):487-91.
Guo, W. W., Li, J., Yu, J. M., Luo, Y. Y., Liu, H., Zheng, L. Q., Buaijiaer, H., Li, X. K., & Hu, D. Y. (2007). [The relationship of ankle brachial index to all-cause and cardiovascular disease mortality in Chinese male patients with hypertension]. Zhonghua Yu Fang Yi Xue Za Zhi [Chinese Journal of Preventive Medicine], 41(6), 487-91.
Guo WW, et al. [The Relationship of Ankle Brachial Index to All-cause and Cardiovascular Disease Mortality in Chinese Male Patients With Hypertension]. Zhonghua Yu Fang Yi Xue Za Zhi. 2007;41(6):487-91. PubMed PMID: 18399131.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [The relationship of ankle brachial index to all-cause and cardiovascular disease mortality in Chinese male patients with hypertension]. AU - Guo,Wei-Wei, AU - Li,Jue, AU - Yu,Jin-Ming, AU - Luo,Ying-Yi, AU - Liu,Hao, AU - Zheng,Li-Qiang, AU - Buaijiaer,Hasimu, AU - Li,Xian-Kai, AU - Hu,Da-Yi, PY - 2008/4/11/pubmed PY - 2009/5/15/medline PY - 2008/4/11/entrez SP - 487 EP - 91 JF - Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] JO - Zhonghua Yu Fang Yi Xue Za Zhi VL - 41 IS - 6 N2 - OBJECTIVE: To evaluate the risk factors for peripheral arterial disease (PAD) and the relationship of low ankle brachial index (ABI) to all-cause and cardiovascular disease (CVD) mortality in Chinese male patients with hypertension. METHODS: The data of 1606 male participants with hypertension from the eight hospitals in Beijing and Shanghai were analyzed. ABI was ascertained at baseline by measuring the systolic pressures on bilateral brachial and tibial arteries. ABI < or = 0.9 was used as the diagnostic criteria for PAD identification. The follow-up survey was conducted from November 2005 to January 2006. RESULTS: Of 1606 male participants with hypertension at baseline, 406 (25.3%) were in low-ABI group and 1200 (74.7%) were in normal-ABI group. Older age, TC, history of diabetes, history of smoking and 2-grade hypertension were associated with low ABI in male patients with hypertension. During the (12.87 +/- 2.94) months follow-up, there were 153 deaths. Of which, 62 were attributable to CVD. Low ABI was associated with adjusted all-cause and CVD mortality risk of 1.728 (1.223-2.441) and 2.388 (1.409-4.046) respectively in Cox regression models. Rate of survival for the low-ABI group was significantly worse than for the normal-ABI group. The risk of all-cause and CVD mortality was increased with the decline of ABI. CONCLUSION: Low ABI is independently associated with the high risks of all-cause and CVD mortality in Chinese male patients with hypertension. The utility of ABI as a tool for predicting mortality in the patients with hypertension should be popularized. SN - 0253-9624 UR - https://www.unboundmedicine.com/medline/citation/18399131/[The_relationship_of_ankle_brachial_index_to_all_cause_and_cardiovascular_disease_mortality_in_Chinese_male_patients_with_hypertension]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0253-9624&amp;year=2007&amp;vol=41&amp;issue=6&amp;fpage=487 DB - PRIME DP - Unbound Medicine ER -