Tags

Type your tag names separated by a space and hit enter

Home fortification of complementary foods with micronutrient supplements is well accepted and has positive effects on infant iron status in Ghana.
Am J Clin Nutr. 2008 Apr; 87(4):929-38.AJ

Abstract

BACKGROUND

Micronutrient deficiencies are common during infancy, and optimal approaches for their prevention need to be identified.

OBJECTIVE

The objective was to compare the efficacy and acceptability of Sprinkles (SP), crushable Nutritabs (NT), and fat-based Nutributter (NB; 108 kcal/d), which provide 6, 16, and 19 vitamins and minerals, respectively, when used for home fortification of complementary foods.

DESIGN

Ghanaian infants were randomly assigned to receive SP (n = 105), NT (n = 105), or NB (n = 103) daily from 6 to 12 mo of age. We assessed dietary intake, morbidity, and compliance weekly. Hemoglobin and plasma ferritin, TfR, C-reactive protein, and zinc were measured at 6 and 12 mo. We used an exit interview to assess acceptability. A randomly selected control group of infants who received no intervention (NI; n = 96) were assessed at 12 mo.

RESULTS

All supplements were well accepted, and the mean percentage of days that supplements were consumed (87%) did not differ between groups. At 12 mo, all 3 intervention groups had significantly higher ferritin and lower TfR concentrations than did the NI control group. Mean (+/- SD) hemoglobin was significantly higher in NT (112 +/- 14 g/L) and NB (114 +/- 14 g/L) but not in SP (110 +/- 14 g/L) infants than in NI infants (106 +/- 14 g/L). The prevalence of iron deficiency anemia was 31% in the NI control group compared with 10% in the intervention groups combined (P < 0.0001).

CONCLUSION

All 3 options for home fortification of complementary foods are effective for reducing the prevalence of iron deficiency in such populations.

Authors+Show Affiliations

Program in International and Community Nutrition, University of California, Davis, CA 95616-8669, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

18400716

Citation

Adu-Afarwuah, Seth, et al. "Home Fortification of Complementary Foods With Micronutrient Supplements Is Well Accepted and Has Positive Effects On Infant Iron Status in Ghana." The American Journal of Clinical Nutrition, vol. 87, no. 4, 2008, pp. 929-38.
Adu-Afarwuah S, Lartey A, Brown KH, et al. Home fortification of complementary foods with micronutrient supplements is well accepted and has positive effects on infant iron status in Ghana. Am J Clin Nutr. 2008;87(4):929-38.
Adu-Afarwuah, S., Lartey, A., Brown, K. H., Zlotkin, S., Briend, A., & Dewey, K. G. (2008). Home fortification of complementary foods with micronutrient supplements is well accepted and has positive effects on infant iron status in Ghana. The American Journal of Clinical Nutrition, 87(4), 929-38.
Adu-Afarwuah S, et al. Home Fortification of Complementary Foods With Micronutrient Supplements Is Well Accepted and Has Positive Effects On Infant Iron Status in Ghana. Am J Clin Nutr. 2008;87(4):929-38. PubMed PMID: 18400716.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Home fortification of complementary foods with micronutrient supplements is well accepted and has positive effects on infant iron status in Ghana. AU - Adu-Afarwuah,Seth, AU - Lartey,Anna, AU - Brown,Kenneth H, AU - Zlotkin,Stanley, AU - Briend,André, AU - Dewey,Kathryn G, PY - 2008/4/11/pubmed PY - 2008/4/29/medline PY - 2008/4/11/entrez SP - 929 EP - 38 JF - The American journal of clinical nutrition JO - Am J Clin Nutr VL - 87 IS - 4 N2 - BACKGROUND: Micronutrient deficiencies are common during infancy, and optimal approaches for their prevention need to be identified. OBJECTIVE: The objective was to compare the efficacy and acceptability of Sprinkles (SP), crushable Nutritabs (NT), and fat-based Nutributter (NB; 108 kcal/d), which provide 6, 16, and 19 vitamins and minerals, respectively, when used for home fortification of complementary foods. DESIGN: Ghanaian infants were randomly assigned to receive SP (n = 105), NT (n = 105), or NB (n = 103) daily from 6 to 12 mo of age. We assessed dietary intake, morbidity, and compliance weekly. Hemoglobin and plasma ferritin, TfR, C-reactive protein, and zinc were measured at 6 and 12 mo. We used an exit interview to assess acceptability. A randomly selected control group of infants who received no intervention (NI; n = 96) were assessed at 12 mo. RESULTS: All supplements were well accepted, and the mean percentage of days that supplements were consumed (87%) did not differ between groups. At 12 mo, all 3 intervention groups had significantly higher ferritin and lower TfR concentrations than did the NI control group. Mean (+/- SD) hemoglobin was significantly higher in NT (112 +/- 14 g/L) and NB (114 +/- 14 g/L) but not in SP (110 +/- 14 g/L) infants than in NI infants (106 +/- 14 g/L). The prevalence of iron deficiency anemia was 31% in the NI control group compared with 10% in the intervention groups combined (P < 0.0001). CONCLUSION: All 3 options for home fortification of complementary foods are effective for reducing the prevalence of iron deficiency in such populations. SN - 1938-3207 UR - https://www.unboundmedicine.com/medline/citation/18400716/Home_fortification_of_complementary_foods_with_micronutrient_supplements_is_well_accepted_and_has_positive_effects_on_infant_iron_status_in_Ghana_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/87.4.929 DB - PRIME DP - Unbound Medicine ER -