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Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit.
J Clin Microbiol. 2008 Jun; 46(6):2099-101.JC

Abstract

We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region.

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  • PMC Free PDF
    • Publisher Full Text
    ncbi.nlm.nih.gov
    jcm.asm.org

    Authors+Show Affiliations

    Zárate MS
    Laboratorio de Bacteriología, Micología y Parasitología, Sección de Nefrología, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno CEMIC, Ciudad Autónoma de Buenos Aires, Argentina. sole_z@hotmail.com
    Gales AC
    No affiliation info available
    Picão RC
    No affiliation info available
    Pujol GS
    No affiliation info available
    Lanza A
    No affiliation info available
    Smayevsky J
    No affiliation info available

    MeSH

    Anti-Bacterial AgentsDisease OutbreaksElectrophoresis, Gel, Pulsed-FieldHospital UnitsHumansKidney TransplantationKlebsiella InfectionsKlebsiella oxytocaMicrobial Sensitivity TestsPoint MutationPromoter Regions, Geneticbeta-Lactam Resistancebeta-Lactamases

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    18417660

    Citation

    Zárate, Mariela Soledad, et al. "Outbreak of OXY-2-Producing Klebsiella Oxytoca in a Renal Transplant Unit." Journal of Clinical Microbiology, vol. 46, no. 6, 2008, pp. 2099-101.
    Zárate MS, Gales AC, Picão RC, et al. Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit. J Clin Microbiol. 2008;46(6):2099-101.
    Zárate, M. S., Gales, A. C., Picão, R. C., Pujol, G. S., Lanza, A., & Smayevsky, J. (2008). Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit. Journal of Clinical Microbiology, 46(6), 2099-101. https://doi.org/10.1128/JCM.00194-08
    Zárate MS, et al. Outbreak of OXY-2-Producing Klebsiella Oxytoca in a Renal Transplant Unit. J Clin Microbiol. 2008;46(6):2099-101. PubMed PMID: 18417660.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Outbreak of OXY-2-Producing Klebsiella oxytoca in a renal transplant unit. AU - Zárate,Mariela Soledad, AU - Gales,Ana C, AU - Picão,Renata C, AU - Pujol,Gervasio Soler, AU - Lanza,Alejandra, AU - Smayevsky,Jorgelina, Y1 - 2008/04/16/ PY - 2008/4/18/pubmed PY - 2008/7/24/medline PY - 2008/4/18/entrez SP - 2099 EP - 101 JF - Journal of clinical microbiology JO - J. Clin. Microbiol. VL - 46 IS - 6 N2 - We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region. SN - 1098-660X UR - https://www.unboundmedicine.com/medline/citation/18417660/Outbreak_of_OXY_2_Producing_Klebsiella_oxytoca_in_a_renal_transplant_unit_ L2 - http://jcm.asm.org/cgi/pmidlookup?view=long&pmid=18417660 DB - PRIME DP - Unbound Medicine ER -