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Stable aqueous film coating dispersion of zein.
J Colloid Interface Sci. 2008 Jun 15; 322(2):478-84.JC

Abstract

The effects of plasticizers, pH, and electrolytes on film formation and physical stability of aqueous film coating dispersions (pseudolatexes) of zein were evaluated. The influence of plasticizer on film formation mechanism and minimum film-formation temperature (MFT) were monitored by means of hot stage microscopy (HSM). Furthermore, the effects of pH and electrolytes on the short-term physical stability of pseudolatexes were investigated by measuring relative absorbance, zeta potential, and particle size of the dispersions. With aqueous coating dispersions of zein, stages of film formation were identified. The dispersions plasticized with 20% (w/w) PEG 400 or glycerol formed mechanically strong and flexible films with the lowest glass transition temperature (T(g)). Physical stability of the aqueous zein dispersions was dependent on both pH and electrolyte content. At a pH ranging from 3 to 4, the aqueous dispersions of zein were stable for at least 2 months exhibiting the highest values for zeta potential, the smallest particle size, and a low volume of aggregates. The stable dispersion could be obtained containing a lower concentration of electrolytes (e.g., 10(-5) M). The physical stability of aqueous zein dispersions can be determined by the combined measurements of relative absorbance, zeta potential, and particle size.

Authors+Show Affiliations

Department of Pharmaceutics, Faculty of Pharmacy, Shandong University, 250012 Jinan, PR China. hongxiaguo@sdu.edu.cnNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18420217

Citation

Guo, H X., et al. "Stable Aqueous Film Coating Dispersion of Zein." Journal of Colloid and Interface Science, vol. 322, no. 2, 2008, pp. 478-84.
Guo HX, Heinämäki J, Yliruusi J. Stable aqueous film coating dispersion of zein. J Colloid Interface Sci. 2008;322(2):478-84.
Guo, H. X., Heinämäki, J., & Yliruusi, J. (2008). Stable aqueous film coating dispersion of zein. Journal of Colloid and Interface Science, 322(2), 478-84. https://doi.org/10.1016/j.jcis.2007.11.058
Guo HX, Heinämäki J, Yliruusi J. Stable Aqueous Film Coating Dispersion of Zein. J Colloid Interface Sci. 2008 Jun 15;322(2):478-84. PubMed PMID: 18420217.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Stable aqueous film coating dispersion of zein. AU - Guo,H X, AU - Heinämäki,J, AU - Yliruusi,J, Y1 - 2007/12/14/ PY - 2007/08/22/received PY - 2007/10/28/revised PY - 2007/11/25/accepted PY - 2008/4/19/pubmed PY - 2008/8/2/medline PY - 2008/4/19/entrez SP - 478 EP - 84 JF - Journal of colloid and interface science JO - J Colloid Interface Sci VL - 322 IS - 2 N2 - The effects of plasticizers, pH, and electrolytes on film formation and physical stability of aqueous film coating dispersions (pseudolatexes) of zein were evaluated. The influence of plasticizer on film formation mechanism and minimum film-formation temperature (MFT) were monitored by means of hot stage microscopy (HSM). Furthermore, the effects of pH and electrolytes on the short-term physical stability of pseudolatexes were investigated by measuring relative absorbance, zeta potential, and particle size of the dispersions. With aqueous coating dispersions of zein, stages of film formation were identified. The dispersions plasticized with 20% (w/w) PEG 400 or glycerol formed mechanically strong and flexible films with the lowest glass transition temperature (T(g)). Physical stability of the aqueous zein dispersions was dependent on both pH and electrolyte content. At a pH ranging from 3 to 4, the aqueous dispersions of zein were stable for at least 2 months exhibiting the highest values for zeta potential, the smallest particle size, and a low volume of aggregates. The stable dispersion could be obtained containing a lower concentration of electrolytes (e.g., 10(-5) M). The physical stability of aqueous zein dispersions can be determined by the combined measurements of relative absorbance, zeta potential, and particle size. SN - 0021-9797 UR - https://www.unboundmedicine.com/medline/citation/18420217/Stable_aqueous_film_coating_dispersion_of_zein_ DB - PRIME DP - Unbound Medicine ER -