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Calcium and dairy product modulation of lipid utilization and energy expenditure.
Obesity (Silver Spring). 2008 Jul; 16(7):1566-72.O

Abstract

OBJECTIVE

The purpose of this study was to investigate the impact of dietary calcium or dairy product intake on total energy expenditure (TEE), fat oxidation, and thermic effect of a meal (TEM) during a weight loss trial.

METHODS AND PROCEDURES

The intervention included a prescribed 500-kcal deficit diet in a randomized placebo-controlled calcium or dairy product intervention employing twenty-four 18 to 31-year-old (22.2+/-3.1 years, mean +/- s.d.) overweight women (75.5+/-9.6 kg). TEM and fat oxidation were measured using respiratory gas exchange after a meal challenge, and TEE was measured by doubly labeled water. Fat mass (FM) and lean mass (fat-free mass (FFM)) were measured by dual-energy X-ray absorptiometry. Subjects were randomized into one of these three intervention groups: (i) placebo (<800 mg/day calcium intake); (ii) 900 mg/day calcium supplement; (iii) three servings of dairy products/day to achieve an additional 900 mg/day.

RESULTS

There were no group effects observed in change in TEE; however, a group effect was observed for fat oxidation after adjusting for FFM (P=0.02). The treatment effect was due to an increase in fat oxidation in the calcium-supplemented group of 1.5+/-0.6 g/h, P=0.02. Baseline 25-hydroxyvitamin D (25OHD) was positively correlated with TEM (R=0.31, P=0.004), and trended toward a correlation with fat oxidation (P=0.06), independent of group assignment. Finally, the change in log parathyroid hormone (PTH) was positively correlated with the change in trunk FM (R=0.27, P=0.03).

DISCUSSION

These results support that calcium intake increases fat oxidation, but does not change TEE and that adequate vitamin D status may enhance TEM and fat oxidation.

Authors+Show Affiliations

Interdepartmental Nutrition Program, Purdue University, West Lafayette, Indiana, USA. dteegard@pudue.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18421269

Citation

Teegarden, Dorothy, et al. "Calcium and Dairy Product Modulation of Lipid Utilization and Energy Expenditure." Obesity (Silver Spring, Md.), vol. 16, no. 7, 2008, pp. 1566-72.
Teegarden D, White KM, Lyle RM, et al. Calcium and dairy product modulation of lipid utilization and energy expenditure. Obesity (Silver Spring). 2008;16(7):1566-72.
Teegarden, D., White, K. M., Lyle, R. M., Zemel, M. B., Van Loan, M. D., Matkovic, V., Craig, B. A., & Schoeller, D. A. (2008). Calcium and dairy product modulation of lipid utilization and energy expenditure. Obesity (Silver Spring, Md.), 16(7), 1566-72. https://doi.org/10.1038/oby.2008.232
Teegarden D, et al. Calcium and Dairy Product Modulation of Lipid Utilization and Energy Expenditure. Obesity (Silver Spring). 2008;16(7):1566-72. PubMed PMID: 18421269.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Calcium and dairy product modulation of lipid utilization and energy expenditure. AU - Teegarden,Dorothy, AU - White,Kimberly M, AU - Lyle,Roseann M, AU - Zemel,Michael B, AU - Van Loan,Marta D, AU - Matkovic,Velimir, AU - Craig,Bruce A, AU - Schoeller,Dale A, Y1 - 2008/04/17/ PY - 2008/4/19/pubmed PY - 2008/9/16/medline PY - 2008/4/19/entrez SP - 1566 EP - 72 JF - Obesity (Silver Spring, Md.) JO - Obesity (Silver Spring) VL - 16 IS - 7 N2 - OBJECTIVE: The purpose of this study was to investigate the impact of dietary calcium or dairy product intake on total energy expenditure (TEE), fat oxidation, and thermic effect of a meal (TEM) during a weight loss trial. METHODS AND PROCEDURES: The intervention included a prescribed 500-kcal deficit diet in a randomized placebo-controlled calcium or dairy product intervention employing twenty-four 18 to 31-year-old (22.2+/-3.1 years, mean +/- s.d.) overweight women (75.5+/-9.6 kg). TEM and fat oxidation were measured using respiratory gas exchange after a meal challenge, and TEE was measured by doubly labeled water. Fat mass (FM) and lean mass (fat-free mass (FFM)) were measured by dual-energy X-ray absorptiometry. Subjects were randomized into one of these three intervention groups: (i) placebo (<800 mg/day calcium intake); (ii) 900 mg/day calcium supplement; (iii) three servings of dairy products/day to achieve an additional 900 mg/day. RESULTS: There were no group effects observed in change in TEE; however, a group effect was observed for fat oxidation after adjusting for FFM (P=0.02). The treatment effect was due to an increase in fat oxidation in the calcium-supplemented group of 1.5+/-0.6 g/h, P=0.02. Baseline 25-hydroxyvitamin D (25OHD) was positively correlated with TEM (R=0.31, P=0.004), and trended toward a correlation with fat oxidation (P=0.06), independent of group assignment. Finally, the change in log parathyroid hormone (PTH) was positively correlated with the change in trunk FM (R=0.27, P=0.03). DISCUSSION: These results support that calcium intake increases fat oxidation, but does not change TEE and that adequate vitamin D status may enhance TEM and fat oxidation. SN - 1930-7381 UR - https://www.unboundmedicine.com/medline/citation/18421269/Calcium_and_dairy_product_modulation_of_lipid_utilization_and_energy_expenditure_ L2 - https://doi.org/10.1038/oby.2008.232 DB - PRIME DP - Unbound Medicine ER -