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[Prognostic factors in rectal cancer].
Vopr Onkol. 1991; 37(9-10):977-81.VO

Abstract

Morphologic type of growth of rectal adenocarcinoma was studied in 292 radically operated cases. Diffuse pattern of growth was established in 86.7% of patients. Mean five-year survival rate was 49.1 +/- 3.9%. Five-year survival rate was 88.2 +/- 9.1% in cases of tumor invading less than one-third of circumference of the intestinal wall, 45.1 +/- 4.0% in those with invasion of the total wall circumference, 83.3 +/- 6.1%--infiltration of all mucosa and submucosa, 39.4 +/- 4.8%--invasion of the entire wall thickness, 31.5 +/- 6.3%--in patients with histologically proven regional metastases, 58.1 +/- 4.8%--in metastasis-free cases, 70.9 +/- 8.1%--in patients with intermediate type of tumor growth with tissue stratification predominating and 43.8 +/- 4.4%--in those with diffusely growing tumors. In a correlation analysis, regional metastases (correlation coefficient K = 0.25), depth of invasion of the intestinal wall (K = 0.24), morphologic pattern of growth (K = 0.22) and length of the intestinal wall invaded (K = 0.20) were shown to influence prognosis most apparently (P < 0.01). Morphologic pattern of growth should, therefore, be considered a prognostic factor.

Authors

Koshchug SD
No affiliation info available
Iakovleva NI
No affiliation info available
Kolod'ko VV
No affiliation info available
Zhukovskiĭ KP
No affiliation info available

MeSH

AdenocarcinomaHumansLymphatic MetastasisNeoplasm InvasivenessNeoplasm StagingPrognosisRectal NeoplasmsRetrospective Studies

Pub Type(s)

English Abstract
Journal Article

Language

rus

PubMed ID

1842661

Citation

Koshchug, S D., et al. "[Prognostic Factors in Rectal Cancer]." Voprosy Onkologii, vol. 37, no. 9-10, 1991, pp. 977-81.
Koshchug SD, Iakovleva NI, Kolod'ko VV, et al. [Prognostic factors in rectal cancer]. Vopr Onkol. 1991;37(9-10):977-81.
Koshchug, S. D., Iakovleva, N. I., Kolod'ko, V. V., & Zhukovskiĭ, K. P. (1991). [Prognostic factors in rectal cancer]. Voprosy Onkologii, 37(9-10), 977-81.
Koshchug SD, et al. [Prognostic Factors in Rectal Cancer]. Vopr Onkol. 1991;37(9-10):977-81. PubMed PMID: 1842661.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Prognostic factors in rectal cancer]. AU - Koshchug,S D, AU - Iakovleva,N I, AU - Kolod'ko,V V, AU - Zhukovskiĭ,K P, PY - 1991/1/1/pubmed PY - 1991/1/1/medline PY - 1991/1/1/entrez SP - 977 EP - 81 JF - Voprosy onkologii JO - Vopr Onkol VL - 37 IS - 9-10 N2 - Morphologic type of growth of rectal adenocarcinoma was studied in 292 radically operated cases. Diffuse pattern of growth was established in 86.7% of patients. Mean five-year survival rate was 49.1 +/- 3.9%. Five-year survival rate was 88.2 +/- 9.1% in cases of tumor invading less than one-third of circumference of the intestinal wall, 45.1 +/- 4.0% in those with invasion of the total wall circumference, 83.3 +/- 6.1%--infiltration of all mucosa and submucosa, 39.4 +/- 4.8%--invasion of the entire wall thickness, 31.5 +/- 6.3%--in patients with histologically proven regional metastases, 58.1 +/- 4.8%--in metastasis-free cases, 70.9 +/- 8.1%--in patients with intermediate type of tumor growth with tissue stratification predominating and 43.8 +/- 4.4%--in those with diffusely growing tumors. In a correlation analysis, regional metastases (correlation coefficient K = 0.25), depth of invasion of the intestinal wall (K = 0.24), morphologic pattern of growth (K = 0.22) and length of the intestinal wall invaded (K = 0.20) were shown to influence prognosis most apparently (P < 0.01). Morphologic pattern of growth should, therefore, be considered a prognostic factor. SN - 0507-3758 UR - https://www.unboundmedicine.com/medline/citation/1842661/[Prognostic_factors_in_rectal_cancer]_ DB - PRIME DP - Unbound Medicine ER -