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Breast magnetic resonance imaging for preoperative locoregional staging.
Am J Surg. 2008 Sep; 196(3):389-97.AJ

Abstract

BACKGROUND

Breast magnetic resonance imaging (MRI) has been recommended increasingly in the preoperative setting for patients newly diagnosed with malignancy to evaluate tumor extent, multicentricity, and contralateral disease.

METHODS

Results of conventional imaging, breast MRI, and pathology were analyzed from 603 consecutive breast cancer patients who underwent MRI preoperatively. The focus of this retrospective study was imaging-histologic correlation.

RESULTS

Reoperation for positive margins after lumpectomy occurred in 8.8% of patients. Multicentricity was identified by MRI alone in 7.7% of patients, whereas 3.7% were found to have contralateral cancer by MRI. The sensitivity of MRI was 93% in detecting multicentric disease and 88% for contralateral disease, whereas sensitivity for conventional imaging was 46% and 19%, respectively. Unsuspected disease was identified by MRI equally for invasive ductal and ductal carcinoma in situ histology, whereas multicentricity was found more frequently with invasive lobular carcinoma.

CONCLUSIONS

Breast MRI is recommended for preoperative evaluation of the newly diagnosed breast cancer patient.

Authors+Show Affiliations

Department of Surgery, Mercy Health Center, Oklahoma City, OK, USA. ahollingsworth@ok.mercy.netNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18436185

Citation

Hollingsworth, Alan B., et al. "Breast Magnetic Resonance Imaging for Preoperative Locoregional Staging." American Journal of Surgery, vol. 196, no. 3, 2008, pp. 389-97.
Hollingsworth AB, Stough RG, O'Dell CA, et al. Breast magnetic resonance imaging for preoperative locoregional staging. Am J Surg. 2008;196(3):389-97.
Hollingsworth, A. B., Stough, R. G., O'Dell, C. A., & Brekke, C. E. (2008). Breast magnetic resonance imaging for preoperative locoregional staging. American Journal of Surgery, 196(3), 389-97. https://doi.org/10.1016/j.amjsurg.2007.10.009
Hollingsworth AB, et al. Breast Magnetic Resonance Imaging for Preoperative Locoregional Staging. Am J Surg. 2008;196(3):389-97. PubMed PMID: 18436185.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Breast magnetic resonance imaging for preoperative locoregional staging. AU - Hollingsworth,Alan B, AU - Stough,Rebecca G, AU - O'Dell,Carol A, AU - Brekke,Charles E, Y1 - 2008/04/23/ PY - 2007/06/18/received PY - 2007/10/22/revised PY - 2007/10/22/accepted PY - 2008/4/26/pubmed PY - 2008/9/17/medline PY - 2008/4/26/entrez SP - 389 EP - 97 JF - American journal of surgery JO - Am J Surg VL - 196 IS - 3 N2 - BACKGROUND: Breast magnetic resonance imaging (MRI) has been recommended increasingly in the preoperative setting for patients newly diagnosed with malignancy to evaluate tumor extent, multicentricity, and contralateral disease. METHODS: Results of conventional imaging, breast MRI, and pathology were analyzed from 603 consecutive breast cancer patients who underwent MRI preoperatively. The focus of this retrospective study was imaging-histologic correlation. RESULTS: Reoperation for positive margins after lumpectomy occurred in 8.8% of patients. Multicentricity was identified by MRI alone in 7.7% of patients, whereas 3.7% were found to have contralateral cancer by MRI. The sensitivity of MRI was 93% in detecting multicentric disease and 88% for contralateral disease, whereas sensitivity for conventional imaging was 46% and 19%, respectively. Unsuspected disease was identified by MRI equally for invasive ductal and ductal carcinoma in situ histology, whereas multicentricity was found more frequently with invasive lobular carcinoma. CONCLUSIONS: Breast MRI is recommended for preoperative evaluation of the newly diagnosed breast cancer patient. SN - 1879-1883 UR - https://www.unboundmedicine.com/medline/citation/18436185/Breast_magnetic_resonance_imaging_for_preoperative_locoregional_staging_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9610(08)00156-6 DB - PRIME DP - Unbound Medicine ER -