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Vulvar leiomyosarcoma in Bartholin's gland area: a case report and literature review.
Arch Gynecol Obstet. 2009 Feb; 279(2):171-4.AG

Abstract

BACKGROUND

Malignant tumours of the vulvar soft tissue are very uncommon. When localized in the Bartholin's gland area these tumours can be mistaken for benign lesions, leading to a delayed diagnosis.

CASE

A 52-year-old woman presenting with a vulvar nodule, which was diagnosed as a Bartholin's gland cyst and was referred to the hospital for surgical excision of the lesion. Pathologist report informed of a 6 cm diameter leiomyosarcoma of the vulva with compromised resection margins; extension studies did not suggest any additional lesions and radical hemivulvectomy with ipsilateral inguinal lymphadenectomy was performed. The patient subsequently received radiotherapy and chemotherapy. Twelve months later, a local recurrence was diagnosed and was removed surgically. After 4 years of follow-up the patient remains disease free.

CONCLUSION

Any vulvar lesion with unusual characteristics or insidious evolution in labia majora or Bartholin's glands area should be carefully and promptly studied. This is particularly important in order to perform an effective surgical treatment in cases of leiomyosarcoma.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, University Hospital Puerta del Mar, Avenida Ana de Viya 21, Cádiz, Spain. fgbugatto@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Review

Language

eng

PubMed ID

18437406

Citation

González-Bugatto, F, et al. "Vulvar Leiomyosarcoma in Bartholin's Gland Area: a Case Report and Literature Review." Archives of Gynecology and Obstetrics, vol. 279, no. 2, 2009, pp. 171-4.
González-Bugatto F, Añón-Requena MJ, López-Guerrero MA, et al. Vulvar leiomyosarcoma in Bartholin's gland area: a case report and literature review. Arch Gynecol Obstet. 2009;279(2):171-4.
González-Bugatto, F., Añón-Requena, M. J., López-Guerrero, M. A., Báez-Perea, J. M., Bartha, J. L., & Hervías-Vivancos, B. (2009). Vulvar leiomyosarcoma in Bartholin's gland area: a case report and literature review. Archives of Gynecology and Obstetrics, 279(2), 171-4. https://doi.org/10.1007/s00404-008-0652-1
González-Bugatto F, et al. Vulvar Leiomyosarcoma in Bartholin's Gland Area: a Case Report and Literature Review. Arch Gynecol Obstet. 2009;279(2):171-4. PubMed PMID: 18437406.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Vulvar leiomyosarcoma in Bartholin's gland area: a case report and literature review. AU - González-Bugatto,F, AU - Añón-Requena,M J, AU - López-Guerrero,M A, AU - Báez-Perea,J M, AU - Bartha,J L, AU - Hervías-Vivancos,B, Y1 - 2008/04/24/ PY - 2008/02/21/received PY - 2008/04/07/accepted PY - 2008/4/26/pubmed PY - 2009/4/4/medline PY - 2008/4/26/entrez SP - 171 EP - 4 JF - Archives of gynecology and obstetrics JO - Arch Gynecol Obstet VL - 279 IS - 2 N2 - BACKGROUND: Malignant tumours of the vulvar soft tissue are very uncommon. When localized in the Bartholin's gland area these tumours can be mistaken for benign lesions, leading to a delayed diagnosis. CASE: A 52-year-old woman presenting with a vulvar nodule, which was diagnosed as a Bartholin's gland cyst and was referred to the hospital for surgical excision of the lesion. Pathologist report informed of a 6 cm diameter leiomyosarcoma of the vulva with compromised resection margins; extension studies did not suggest any additional lesions and radical hemivulvectomy with ipsilateral inguinal lymphadenectomy was performed. The patient subsequently received radiotherapy and chemotherapy. Twelve months later, a local recurrence was diagnosed and was removed surgically. After 4 years of follow-up the patient remains disease free. CONCLUSION: Any vulvar lesion with unusual characteristics or insidious evolution in labia majora or Bartholin's glands area should be carefully and promptly studied. This is particularly important in order to perform an effective surgical treatment in cases of leiomyosarcoma. SN - 1432-0711 UR - https://www.unboundmedicine.com/medline/citation/18437406/Vulvar_leiomyosarcoma_in_Bartholin's_gland_area:_a_case_report_and_literature_review_ L2 - https://dx.doi.org/10.1007/s00404-008-0652-1 DB - PRIME DP - Unbound Medicine ER -