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Long-term benefits of Roux-en-Y pouch reconstruction after total gastrectomy: a randomized trial.
Ann Surg. 2008 May; 247(5):759-65.AnnS

Abstract

OBJECTIVE

Roux-en-Y reconstruction with and without jejunal pouch was compared in a randomized controlled trial to identify the optimal reconstruction procedure in terms of quality of life.

BACKGROUND DATA

Randomized trials comparing techniques of reconstruction after total gastrectomy have shown controversial results.

METHODS

One hundred and thirty-eight patients with gastric cancer were intraoperatively randomized for Roux-en-Y reconstruction with pouch (n = 71) or without pouch (n = 67) after gastrectomy and stratified into curative or palliative resection. Intra- and postoperative complications were recorded. Body weight and quality of life were determined every 6 months with a follow-up of up to 12 years.

RESULTS

Both groups were comparable for age, sex, incidence of concomitant disease, and staging. There were no differences in operative time, postoperative complications, and mortality. Short- and long-term weight loss was similar in both groups. In the first postoperative year, there were no benefits of pouch reconstruction in terms of quality of life, independent of the resection status. In the third, fourth, and fifth year after surgery quality of life was significantly improved for patients with a pouch.

CONCLUSIONS

Roux-en-Y pouch reconstruction after gastrectomy is simple to perform and safe. Long-term survivors benefit from pouch reconstruction. Therefore, a pouch is recommended for patients with a good prognosis.

Authors+Show Affiliations

Department of Surgery, University of Wuerzburg, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

18438112

Citation

Fein, Martin, et al. "Long-term Benefits of Roux-en-Y Pouch Reconstruction After Total Gastrectomy: a Randomized Trial." Annals of Surgery, vol. 247, no. 5, 2008, pp. 759-65.
Fein M, Fuchs KH, Thalheimer A, et al. Long-term benefits of Roux-en-Y pouch reconstruction after total gastrectomy: a randomized trial. Ann Surg. 2008;247(5):759-65.
Fein, M., Fuchs, K. H., Thalheimer, A., Freys, S. M., Heimbucher, J., & Thiede, A. (2008). Long-term benefits of Roux-en-Y pouch reconstruction after total gastrectomy: a randomized trial. Annals of Surgery, 247(5), 759-65. https://doi.org/10.1097/SLA.0b013e318167748c
Fein M, et al. Long-term Benefits of Roux-en-Y Pouch Reconstruction After Total Gastrectomy: a Randomized Trial. Ann Surg. 2008;247(5):759-65. PubMed PMID: 18438112.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Long-term benefits of Roux-en-Y pouch reconstruction after total gastrectomy: a randomized trial. AU - Fein,Martin, AU - Fuchs,Karl-Hermann, AU - Thalheimer,Andreas, AU - Freys,Stephan M, AU - Heimbucher,Johannes, AU - Thiede,Arnulf, PY - 2008/4/29/pubmed PY - 2008/6/5/medline PY - 2008/4/29/entrez SP - 759 EP - 65 JF - Annals of surgery JO - Ann Surg VL - 247 IS - 5 N2 - OBJECTIVE: Roux-en-Y reconstruction with and without jejunal pouch was compared in a randomized controlled trial to identify the optimal reconstruction procedure in terms of quality of life. BACKGROUND DATA: Randomized trials comparing techniques of reconstruction after total gastrectomy have shown controversial results. METHODS: One hundred and thirty-eight patients with gastric cancer were intraoperatively randomized for Roux-en-Y reconstruction with pouch (n = 71) or without pouch (n = 67) after gastrectomy and stratified into curative or palliative resection. Intra- and postoperative complications were recorded. Body weight and quality of life were determined every 6 months with a follow-up of up to 12 years. RESULTS: Both groups were comparable for age, sex, incidence of concomitant disease, and staging. There were no differences in operative time, postoperative complications, and mortality. Short- and long-term weight loss was similar in both groups. In the first postoperative year, there were no benefits of pouch reconstruction in terms of quality of life, independent of the resection status. In the third, fourth, and fifth year after surgery quality of life was significantly improved for patients with a pouch. CONCLUSIONS: Roux-en-Y pouch reconstruction after gastrectomy is simple to perform and safe. Long-term survivors benefit from pouch reconstruction. Therefore, a pouch is recommended for patients with a good prognosis. SN - 1528-1140 UR - https://www.unboundmedicine.com/medline/citation/18438112/Long_term_benefits_of_Roux_en_Y_pouch_reconstruction_after_total_gastrectomy:_a_randomized_trial_ L2 - https://Insights.ovid.com/pubmed?pmid=18438112 DB - PRIME DP - Unbound Medicine ER -