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The failure of a nerve sparing template to improve urinary continence after radical prostatectomy: attention to study design.
Urol Oncol. 2009 Jul-Aug; 27(4):358-62.UO

Abstract

PURPOSE

To accurately assess the relationship between nerve sparing radical prostatectomy and urinary continence using an anonymous validated survey in men undergoing surgical treatment for prostate cancer.

MATERIALS AND METHODS

From September 1999 to February 2006, men undergoing radical prostatectomy (RP) by one surgeon were given the UCLA Prostate Cancer Index to complete preop, and then annually thereafter to 2 years. We have 285 men who have completed the pre-op and year 1 and /or year 2 surveys. Continence was defined as requiring "no pads" on the survey. Analysis was based on attempted nerve sparing status of the surgery; none, unilateral, or bilateral. Subgroup analysis was then performed on successful nerve sparing surgery, defined as men responding they have an erection "firm enough for intercourse."

RESULTS

Overall continence rates were 81% at year 1 and 87% at year 2. Attempted nerve sparing surgery, or successful nerve sparing surgery, did not result in better rates of continence than non-nerve sparing surgery.

CONCLUSIONS

Using a validated survey with anonymous data collection, we found no improvement in continence, defined as pad-free, with attempted or successful nerve sparing RP. Based on our study, the goal of improving urinary outcomes should not be used as a justification for a nerve sparing template at radical prostatectomy.

Authors+Show Affiliations

Department of Surgery, Section of Urology, Tucson Medical Center and Biometry Unit, Arizona Cancer Center, Arizona Health Sciences Center, Tucson, AZ 85712, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18439849

Citation

Tzou, David T., et al. "The Failure of a Nerve Sparing Template to Improve Urinary Continence After Radical Prostatectomy: Attention to Study Design." Urologic Oncology, vol. 27, no. 4, 2009, pp. 358-62.
Tzou DT, Dalkin BL, Christopher BA, et al. The failure of a nerve sparing template to improve urinary continence after radical prostatectomy: attention to study design. Urol Oncol. 2009;27(4):358-62.
Tzou, D. T., Dalkin, B. L., Christopher, B. A., & Cui, H. (2009). The failure of a nerve sparing template to improve urinary continence after radical prostatectomy: attention to study design. Urologic Oncology, 27(4), 358-62. https://doi.org/10.1016/j.urolonc.2008.01.013
Tzou DT, et al. The Failure of a Nerve Sparing Template to Improve Urinary Continence After Radical Prostatectomy: Attention to Study Design. Urol Oncol. 2009 Jul-Aug;27(4):358-62. PubMed PMID: 18439849.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The failure of a nerve sparing template to improve urinary continence after radical prostatectomy: attention to study design. AU - Tzou,David T, AU - Dalkin,Bruce L, AU - Christopher,Bea Anne, AU - Cui,Haiyan, Y1 - 2008/04/24/ PY - 2007/11/20/received PY - 2008/01/27/revised PY - 2008/01/31/accepted PY - 2008/4/29/pubmed PY - 2009/9/11/medline PY - 2008/4/29/entrez SP - 358 EP - 62 JF - Urologic oncology JO - Urol Oncol VL - 27 IS - 4 N2 - PURPOSE: To accurately assess the relationship between nerve sparing radical prostatectomy and urinary continence using an anonymous validated survey in men undergoing surgical treatment for prostate cancer. MATERIALS AND METHODS: From September 1999 to February 2006, men undergoing radical prostatectomy (RP) by one surgeon were given the UCLA Prostate Cancer Index to complete preop, and then annually thereafter to 2 years. We have 285 men who have completed the pre-op and year 1 and /or year 2 surveys. Continence was defined as requiring "no pads" on the survey. Analysis was based on attempted nerve sparing status of the surgery; none, unilateral, or bilateral. Subgroup analysis was then performed on successful nerve sparing surgery, defined as men responding they have an erection "firm enough for intercourse." RESULTS: Overall continence rates were 81% at year 1 and 87% at year 2. Attempted nerve sparing surgery, or successful nerve sparing surgery, did not result in better rates of continence than non-nerve sparing surgery. CONCLUSIONS: Using a validated survey with anonymous data collection, we found no improvement in continence, defined as pad-free, with attempted or successful nerve sparing RP. Based on our study, the goal of improving urinary outcomes should not be used as a justification for a nerve sparing template at radical prostatectomy. SN - 1873-2496 UR - https://www.unboundmedicine.com/medline/citation/18439849/The_failure_of_a_nerve_sparing_template_to_improve_urinary_continence_after_radical_prostatectomy:_attention_to_study_design_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1078-1439(08)00034-3 DB - PRIME DP - Unbound Medicine ER -