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Rapidly developing weakness mimicking Guillain-Barré syndrome in beriberi neuropathy: two case reports.
Nutrition. 2008 Jul-Aug; 24(7-8):776-80.N

Abstract

OBJECTIVE

We examined the diagnostic difficulty in thiamine deficiency.

METHODS

We report on two patients with polyneuropathy associated with thiamine deficiency (i.e., beriberi neuropathy) that presented with acute motor symptoms mimicking Guillain-Barré syndrome.

RESULTS

The cause of the thiamine deficiency was associated with gastrectomy to treat cancer in a 46-y-old man and with dietary imbalance in a 33-y-old man. The thiamine deficiency was not related to alcohol intake in either patient. In both patients, the upper and lower extremities showed a rapidly progressive weakness over the course of 1 mo. Muscle weakness in the first patient progressed even after admission to the hospital, and urinary retention, Wernicke's encephalopathy, lactic acidosis, paralytic ileus, and heart failure appeared subsequently. Clinical symptoms in both patients showed improvement after initiation of thiamine administration, although some residual deficit remained.

CONCLUSION

Thiamine deficiency must be actively considered as a possible cause of polyneuropathy, and variability in its clinical features should be taken into consideration.

Authors+Show Affiliations

Department of Neurology, Nagoya University School of Medicine, Nagoya, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18440777

Citation

Koike, Haruki, et al. "Rapidly Developing Weakness Mimicking Guillain-Barré Syndrome in Beriberi Neuropathy: Two Case Reports." Nutrition (Burbank, Los Angeles County, Calif.), vol. 24, no. 7-8, 2008, pp. 776-80.
Koike H, Ito S, Morozumi S, et al. Rapidly developing weakness mimicking Guillain-Barré syndrome in beriberi neuropathy: two case reports. Nutrition. 2008;24(7-8):776-80.
Koike, H., Ito, S., Morozumi, S., Kawagashira, Y., Iijima, M., Hattori, N., Tanaka, F., & Sobue, G. (2008). Rapidly developing weakness mimicking Guillain-Barré syndrome in beriberi neuropathy: two case reports. Nutrition (Burbank, Los Angeles County, Calif.), 24(7-8), 776-80. https://doi.org/10.1016/j.nut.2008.02.022
Koike H, et al. Rapidly Developing Weakness Mimicking Guillain-Barré Syndrome in Beriberi Neuropathy: Two Case Reports. Nutrition. 2008 Jul-Aug;24(7-8):776-80. PubMed PMID: 18440777.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Rapidly developing weakness mimicking Guillain-Barré syndrome in beriberi neuropathy: two case reports. AU - Koike,Haruki, AU - Ito,Shinji, AU - Morozumi,Saori, AU - Kawagashira,Yuichi, AU - Iijima,Masahiro, AU - Hattori,Naoki, AU - Tanaka,Fumiaki, AU - Sobue,Gen, Y1 - 2008/04/28/ PY - 2007/11/02/received PY - 2008/02/13/revised PY - 2008/02/22/accepted PY - 2008/4/29/pubmed PY - 2008/9/23/medline PY - 2008/4/29/entrez SP - 776 EP - 80 JF - Nutrition (Burbank, Los Angeles County, Calif.) JO - Nutrition VL - 24 IS - 7-8 N2 - OBJECTIVE: We examined the diagnostic difficulty in thiamine deficiency. METHODS: We report on two patients with polyneuropathy associated with thiamine deficiency (i.e., beriberi neuropathy) that presented with acute motor symptoms mimicking Guillain-Barré syndrome. RESULTS: The cause of the thiamine deficiency was associated with gastrectomy to treat cancer in a 46-y-old man and with dietary imbalance in a 33-y-old man. The thiamine deficiency was not related to alcohol intake in either patient. In both patients, the upper and lower extremities showed a rapidly progressive weakness over the course of 1 mo. Muscle weakness in the first patient progressed even after admission to the hospital, and urinary retention, Wernicke's encephalopathy, lactic acidosis, paralytic ileus, and heart failure appeared subsequently. Clinical symptoms in both patients showed improvement after initiation of thiamine administration, although some residual deficit remained. CONCLUSION: Thiamine deficiency must be actively considered as a possible cause of polyneuropathy, and variability in its clinical features should be taken into consideration. SN - 0899-9007 UR - https://www.unboundmedicine.com/medline/citation/18440777/Rapidly_developing_weakness_mimicking_Guillain_Barré_syndrome_in_beriberi_neuropathy:_two_case_reports_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0899-9007(08)00114-7 DB - PRIME DP - Unbound Medicine ER -