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Impairments in cognition across the spectrum of psychiatric disorders: evidence from a Swedish conscript cohort.
Schizophr Bull. 2008 Nov; 34(6):1035-41.SB

Abstract

It is well established that cognitive deficits are an almost invariable component of the schizophrenia syndrome. Much less is known about the association of cognitive deficits and the range of psychiatric disorders. The current study made use of a Swedish conscript cohort which included an IQ assessment and full psychiatric evaluation at conscription of all 18- to 19-year-old males. It was found that reduced intellectual functioning was found in association with psychosis and neurotic disorders including depression, personality disorders, alcoholism, and drug dependence. The effect was particularly strong for alcoholism. This presumably represents a combination of premorbid deficits (as demonstrated in those who developed schizophrenia some years later) plus coincident impairments. The direction of causality of this latter association is likely to be both forward and reverse. Different cognitive subtests showed varied strengths of association: "mechanical ability/knowledge," which might reflect planning and reasoning more than the other subtests, had the strongest effect. Cognitive deficits are widespread in psychiatric disorders and should be taken into account in clinical interactions.

Authors+Show Affiliations

Section of Cognitive Neuropsychiatry, Institute of Psychiatry, King's College, London, UK. a.david@iop.kcl.ac.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18441331

Citation

David, Anthony S., et al. "Impairments in Cognition Across the Spectrum of Psychiatric Disorders: Evidence From a Swedish Conscript Cohort." Schizophrenia Bulletin, vol. 34, no. 6, 2008, pp. 1035-41.
David AS, Zammit S, Lewis G, et al. Impairments in cognition across the spectrum of psychiatric disorders: evidence from a Swedish conscript cohort. Schizophr Bull. 2008;34(6):1035-41.
David, A. S., Zammit, S., Lewis, G., Dalman, C., & Allebeck, P. (2008). Impairments in cognition across the spectrum of psychiatric disorders: evidence from a Swedish conscript cohort. Schizophrenia Bulletin, 34(6), 1035-41. https://doi.org/10.1093/schbul/sbn028
David AS, et al. Impairments in Cognition Across the Spectrum of Psychiatric Disorders: Evidence From a Swedish Conscript Cohort. Schizophr Bull. 2008;34(6):1035-41. PubMed PMID: 18441331.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impairments in cognition across the spectrum of psychiatric disorders: evidence from a Swedish conscript cohort. AU - David,Anthony S, AU - Zammit,Stanley, AU - Lewis,Glyn, AU - Dalman,Christina, AU - Allebeck,Peter, Y1 - 2008/04/25/ PY - 2008/4/29/pubmed PY - 2009/2/4/medline PY - 2008/4/29/entrez SP - 1035 EP - 41 JF - Schizophrenia bulletin JO - Schizophr Bull VL - 34 IS - 6 N2 - It is well established that cognitive deficits are an almost invariable component of the schizophrenia syndrome. Much less is known about the association of cognitive deficits and the range of psychiatric disorders. The current study made use of a Swedish conscript cohort which included an IQ assessment and full psychiatric evaluation at conscription of all 18- to 19-year-old males. It was found that reduced intellectual functioning was found in association with psychosis and neurotic disorders including depression, personality disorders, alcoholism, and drug dependence. The effect was particularly strong for alcoholism. This presumably represents a combination of premorbid deficits (as demonstrated in those who developed schizophrenia some years later) plus coincident impairments. The direction of causality of this latter association is likely to be both forward and reverse. Different cognitive subtests showed varied strengths of association: "mechanical ability/knowledge," which might reflect planning and reasoning more than the other subtests, had the strongest effect. Cognitive deficits are widespread in psychiatric disorders and should be taken into account in clinical interactions. SN - 0586-7614 UR - https://www.unboundmedicine.com/medline/citation/18441331/Impairments_in_cognition_across_the_spectrum_of_psychiatric_disorders:_evidence_from_a_Swedish_conscript_cohort_ L2 - https://academic.oup.com/schizophreniabulletin/article-lookup/doi/10.1093/schbul/sbn028 DB - PRIME DP - Unbound Medicine ER -