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[A new milk formula: iron bioavailability and effect on prevention of iron deficiency in infants].
Rev Chil Pediatr. 1991 Mar-Apr; 62(2):94-8.RC

Abstract

Iron bioavailability from a modified cow milk, formula (LPM) (which included additional iron as 5 mg/l ferrous sulfate and ascorbic acid, 50 mg/l) was examined in 11 adult women using the extrinsic radioactive tag method. The geometric mean absorption from LPM was 13% (reference dose absorption = 26%). The effect of this formula on iron nutrition of infants was studied in 43 healthy term infants weaned spontaneously before 3 months of age which were given LPM until 9 months of age. Another 45 infants (controls) were fed full fat, non fortified powdered cow's milk (LP) as delivered through the National Complementary Food Program (PNAC-Chile) and additional 45 infants were given fortified a cow's milk formula (LF) with ferrous sulfate (iron: 15 mg/l and ascorbic acid: 100 mg/l). Solid foods (vegetables and meat) were introduced to all these babies from age 4 months. At 9 months of age 4% infants fed LPM had evidence of anemia vs. 2% and 20% of infants given LF and LP formulae respectively. This results suggests that LPM is effective in preventing iron deficiency anemia in infants.

Authors+Show Affiliations

INTA, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

spa

PubMed ID

1844169

Citation

Hertrampf, E, et al. "[A New Milk Formula: Iron Bioavailability and Effect On Prevention of Iron Deficiency in Infants]." Revista Chilena De Pediatria, vol. 62, no. 2, 1991, pp. 94-8.
Hertrampf E, Pizarro F, Pereyra A, et al. [A new milk formula: iron bioavailability and effect on prevention of iron deficiency in infants]. Rev Chil Pediatr. 1991;62(2):94-8.
Hertrampf, E., Pizarro, F., Pereyra, A., & Vega, V. (1991). [A new milk formula: iron bioavailability and effect on prevention of iron deficiency in infants]. Revista Chilena De Pediatria, 62(2), 94-8.
Hertrampf E, et al. [A New Milk Formula: Iron Bioavailability and Effect On Prevention of Iron Deficiency in Infants]. Rev Chil Pediatr. 1991 Mar-Apr;62(2):94-8. PubMed PMID: 1844169.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A new milk formula: iron bioavailability and effect on prevention of iron deficiency in infants]. AU - Hertrampf,E, AU - Pizarro,F, AU - Pereyra,A, AU - Vega,V, PY - 1991/3/1/pubmed PY - 1991/3/1/medline PY - 1991/3/1/entrez SP - 94 EP - 8 JF - Revista chilena de pediatria JO - Rev Chil Pediatr VL - 62 IS - 2 N2 - Iron bioavailability from a modified cow milk, formula (LPM) (which included additional iron as 5 mg/l ferrous sulfate and ascorbic acid, 50 mg/l) was examined in 11 adult women using the extrinsic radioactive tag method. The geometric mean absorption from LPM was 13% (reference dose absorption = 26%). The effect of this formula on iron nutrition of infants was studied in 43 healthy term infants weaned spontaneously before 3 months of age which were given LPM until 9 months of age. Another 45 infants (controls) were fed full fat, non fortified powdered cow's milk (LP) as delivered through the National Complementary Food Program (PNAC-Chile) and additional 45 infants were given fortified a cow's milk formula (LF) with ferrous sulfate (iron: 15 mg/l and ascorbic acid: 100 mg/l). Solid foods (vegetables and meat) were introduced to all these babies from age 4 months. At 9 months of age 4% infants fed LPM had evidence of anemia vs. 2% and 20% of infants given LF and LP formulae respectively. This results suggests that LPM is effective in preventing iron deficiency anemia in infants. SN - 0370-4106 UR - https://www.unboundmedicine.com/medline/citation/1844169/[A_new_milk_formula:_iron_bioavailability_and_effect_on_prevention_of_iron_deficiency_in_infants]_ L2 - https://medlineplus.gov/iron.html DB - PRIME DP - Unbound Medicine ER -