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Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey.
Autism. 2008 May; 12(3):293-307.A

Abstract

The present study was performed to determine whether acetaminophen (paracetamol) use after the measles-mumps-rubella vaccination could be associated with autistic disorder. This case-control study used the results of an online parental survey conducted from 16 July 2005 to 30 January 2006, consisting of 83 children with autistic disorder and 80 control children. Acetaminophen use after measles-mumps-rubella vaccination was significantly associated with autistic disorder when considering children 5 years of age or less (OR 6.11, 95% CI 1.42-26.3), after limiting cases to children with regression in development (OR 3.97, 95% CI 1.11-14.3), and when considering only children who had post-vaccination sequelae (OR 8.23, 95% CI 1.56-43.3), adjusting for age, gender, mother's ethnicity, and the presence of illness concurrent with measles-mumps-rubella vaccination. Ibuprofen use after measles-mumps-rubella vaccination was not associated with autistic disorder. This preliminary study found that acetaminophen use after measles-mumps-rubella vaccination was associated with autistic disorder.

Authors+Show Affiliations

University of California San Diego, USA. Stephen.schultz@med.navy.milNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18445737

Citation

Schultz, Stephen T., et al. "Acetaminophen (paracetamol) Use, Measles-mumps-rubella Vaccination, and Autistic Disorder: the Results of a Parent Survey." Autism : the International Journal of Research and Practice, vol. 12, no. 3, 2008, pp. 293-307.
Schultz ST, Klonoff-Cohen HS, Wingard DL, et al. Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey. Autism. 2008;12(3):293-307.
Schultz, S. T., Klonoff-Cohen, H. S., Wingard, D. L., Akshoomoff, N. A., Macera, C. A., & Ji, M. (2008). Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey. Autism : the International Journal of Research and Practice, 12(3), 293-307. https://doi.org/10.1177/1362361307089518
Schultz ST, et al. Acetaminophen (paracetamol) Use, Measles-mumps-rubella Vaccination, and Autistic Disorder: the Results of a Parent Survey. Autism. 2008;12(3):293-307. PubMed PMID: 18445737.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acetaminophen (paracetamol) use, measles-mumps-rubella vaccination, and autistic disorder: the results of a parent survey. AU - Schultz,Stephen T, AU - Klonoff-Cohen,Hillary S, AU - Wingard,Deborah L, AU - Akshoomoff,Natacha A, AU - Macera,Caroline A, AU - Ji,Ming, PY - 2008/5/1/pubmed PY - 2008/7/9/medline PY - 2008/5/1/entrez SP - 293 EP - 307 JF - Autism : the international journal of research and practice JO - Autism VL - 12 IS - 3 N2 - The present study was performed to determine whether acetaminophen (paracetamol) use after the measles-mumps-rubella vaccination could be associated with autistic disorder. This case-control study used the results of an online parental survey conducted from 16 July 2005 to 30 January 2006, consisting of 83 children with autistic disorder and 80 control children. Acetaminophen use after measles-mumps-rubella vaccination was significantly associated with autistic disorder when considering children 5 years of age or less (OR 6.11, 95% CI 1.42-26.3), after limiting cases to children with regression in development (OR 3.97, 95% CI 1.11-14.3), and when considering only children who had post-vaccination sequelae (OR 8.23, 95% CI 1.56-43.3), adjusting for age, gender, mother's ethnicity, and the presence of illness concurrent with measles-mumps-rubella vaccination. Ibuprofen use after measles-mumps-rubella vaccination was not associated with autistic disorder. This preliminary study found that acetaminophen use after measles-mumps-rubella vaccination was associated with autistic disorder. SN - 1362-3613 UR - https://www.unboundmedicine.com/medline/citation/18445737/Acetaminophen__paracetamol__use_measles_mumps_rubella_vaccination_and_autistic_disorder:_the_results_of_a_parent_survey_ L2 - http://journals.sagepub.com/doi/full/10.1177/1362361307089518?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -