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[Current situation and future perspectives for malaria prophylaxis among travellers and military personnel].
Bull Acad Natl Med. 2007 Oct; 191(7):1293-302; discussion 1302-3.BA

Abstract

Malaria remains a major public health problem, both for travellers and for the 40,000 French soldiers deployed each year to endemic areas. Epidemiological data show that imported malaria (IM) is on the increase, and that migrants account for more than 60% of malaria cases notified each year in France. The increase in IM among French military personnel is explained by prematurely terminated chemoprophylaxis on return, repeated short missions, and more cases of P. vivax and P. ovale infection. The choice of chemoprophylaxis depends mainly on the level of chloroquine resistance in the country visited. The atovaquone-proguanil combination is well tolerated and only requires 7 days of intake on return from the endemic area. Doxycycline monohydrate is cheaper and better-tolerated than mefloquine, and is thus preferred for French military personnel. However, its short half-life necessitates very good compliance. Chemoprophylaxis should be combined with vector control measures and with personal protection (impregnated bednets, protective clothing, repellents, and indoor insecticide spraying). The need for these measures should be clearly explained before departure, during the stay, and after return.

Authors+Show Affiliations

Institut de Médecine Tropicale du Service de Santé des armées, Le Pharo, BP : 46, 13998-Marseille armées.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

fre

PubMed ID

18447051

Citation

Touze, Jean-Etienne, et al. "[Current Situation and Future Perspectives for Malaria Prophylaxis Among Travellers and Military Personnel]." Bulletin De l'Academie Nationale De Medecine, vol. 191, no. 7, 2007, pp. 1293-302; discussion 1302-3.
Touze JE, Debonne JM, Boutin JP. [Current situation and future perspectives for malaria prophylaxis among travellers and military personnel]. Bull Acad Natl Med. 2007;191(7):1293-302; discussion 1302-3.
Touze, J. E., Debonne, J. M., & Boutin, J. P. (2007). [Current situation and future perspectives for malaria prophylaxis among travellers and military personnel]. Bulletin De l'Academie Nationale De Medecine, 191(7), 1293-302; discussion 1302-3.
Touze JE, Debonne JM, Boutin JP. [Current Situation and Future Perspectives for Malaria Prophylaxis Among Travellers and Military Personnel]. Bull Acad Natl Med. 2007;191(7):1293-302; discussion 1302-3. PubMed PMID: 18447051.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Current situation and future perspectives for malaria prophylaxis among travellers and military personnel]. AU - Touze,Jean-Etienne, AU - Debonne,Jean-Marc, AU - Boutin,Jean-Paul, PY - 2008/5/2/pubmed PY - 2008/6/27/medline PY - 2008/5/2/entrez SP - 1293-302; discussion 1302-3 JF - Bulletin de l'Academie nationale de medecine JO - Bull Acad Natl Med VL - 191 IS - 7 N2 - Malaria remains a major public health problem, both for travellers and for the 40,000 French soldiers deployed each year to endemic areas. Epidemiological data show that imported malaria (IM) is on the increase, and that migrants account for more than 60% of malaria cases notified each year in France. The increase in IM among French military personnel is explained by prematurely terminated chemoprophylaxis on return, repeated short missions, and more cases of P. vivax and P. ovale infection. The choice of chemoprophylaxis depends mainly on the level of chloroquine resistance in the country visited. The atovaquone-proguanil combination is well tolerated and only requires 7 days of intake on return from the endemic area. Doxycycline monohydrate is cheaper and better-tolerated than mefloquine, and is thus preferred for French military personnel. However, its short half-life necessitates very good compliance. Chemoprophylaxis should be combined with vector control measures and with personal protection (impregnated bednets, protective clothing, repellents, and indoor insecticide spraying). The need for these measures should be clearly explained before departure, during the stay, and after return. SN - 0001-4079 UR - https://www.unboundmedicine.com/medline/citation/18447051/[Current_situation_and_future_perspectives_for_malaria_prophylaxis_among_travellers_and_military_personnel]_ L2 - http://www.diseaseinfosearch.org/result/4415 DB - PRIME DP - Unbound Medicine ER -