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Nervous system Lyme disease.
Infect Dis Clin North Am. 2008 Jun; 22(2):261-74, vi.ID

Abstract

Lyme disease affects the nervous system in about 10% to 15% of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculitis, radicular pain involving a limb or trunk dermatome. Treatment of neuroborreliosis is usually straightforward; oral antibiotics may suffice in many patients. In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit.

Authors+Show Affiliations

Department of Neurosciences, Atlantic Neuroscience Institute & Overlook Hospital, Summit, NJ 07902, USA. john.halperin@atlantichealth.org

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18452800

Citation

Halperin, John J.. "Nervous System Lyme Disease." Infectious Disease Clinics of North America, vol. 22, no. 2, 2008, pp. 261-74, vi.
Halperin JJ. Nervous system Lyme disease. Infect Dis Clin North Am. 2008;22(2):261-74, vi.
Halperin, J. J. (2008). Nervous system Lyme disease. Infectious Disease Clinics of North America, 22(2), 261-74, vi. https://doi.org/10.1016/j.idc.2007.12.009
Halperin JJ. Nervous System Lyme Disease. Infect Dis Clin North Am. 2008;22(2):261-74, vi. PubMed PMID: 18452800.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Nervous system Lyme disease. A1 - Halperin,John J, PY - 2008/5/3/pubmed PY - 2008/7/25/medline PY - 2008/5/3/entrez SP - 261-74, vi JF - Infectious disease clinics of North America JO - Infect. Dis. Clin. North Am. VL - 22 IS - 2 N2 - Lyme disease affects the nervous system in about 10% to 15% of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculitis, radicular pain involving a limb or trunk dermatome. Treatment of neuroborreliosis is usually straightforward; oral antibiotics may suffice in many patients. In severe cases, 2 to 4 weeks of parenteral therapy is necessary. All available evidence indicates that treatment of more than 4 weeks' duration carries substantial risk but minimal if any additional benefit. SN - 0891-5520 UR - https://www.unboundmedicine.com/medline/citation/18452800/Nervous_system_Lyme_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0891-5520(07)00126-2 DB - PRIME DP - Unbound Medicine ER -