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Study on the preparation of collagen-modified silk fibroin films and their properties.
Biomed Mater. 2006 Dec; 1(4):242-6.BM

Abstract

Blended films were prepared from a silk fibroin (SF) solution by adding a small amount of type I collagen (<5%). The mechanical properties of the wet films modified by collagen were improved obviously. The elongation at break reached 42%, and the smaller contact angles revealed that modified films had better hydrophilicity. 1% heparin was also added to modify the SF films to further improve the in vitro antithrombogenecity. The internal structure of the modified SF films was investigated with scanning electron microscopy, x-ray diffraction and Fourier transform infrared attenuated total reflection spectroscopy. The result indicates that the addition of a small amount of collagen and heparin did not change their conformation.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Tang Y
Research Center of Material Science, Beijing Institute of Technology, Bejing 100081, People's Republic of China.
Cao C
No affiliation info available
Ma X
No affiliation info available
Chen C
No affiliation info available
Zhu H
No affiliation info available

MeSH

Biocompatible MaterialsBlood CoagulationCells, CulturedCollagenElasticityFibroinsHeparinHumansMaterials TestingMembranes, ArtificialSilkStress, MechanicalTensile Strength

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18458412

Citation

Tang, Yin, et al. "Study On the Preparation of Collagen-modified Silk Fibroin Films and Their Properties." Biomedical Materials (Bristol, England), vol. 1, no. 4, 2006, pp. 242-6.
Tang Y, Cao C, Ma X, et al. Study on the preparation of collagen-modified silk fibroin films and their properties. Biomed Mater. 2006;1(4):242-6.
Tang, Y., Cao, C., Ma, X., Chen, C., & Zhu, H. (2006). Study on the preparation of collagen-modified silk fibroin films and their properties. Biomedical Materials (Bristol, England), 1(4), 242-6. https://doi.org/10.1088/1748-6041/1/4/010
Tang Y, et al. Study On the Preparation of Collagen-modified Silk Fibroin Films and Their Properties. Biomed Mater. 2006;1(4):242-6. PubMed PMID: 18458412.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Study on the preparation of collagen-modified silk fibroin films and their properties. AU - Tang,Yin, AU - Cao,Chuanbao, AU - Ma,Xilan, AU - Chen,Chen, AU - Zhu,Hesun, Y1 - 2006/12/04/ PY - 2008/5/7/pubmed PY - 2008/5/29/medline PY - 2008/5/7/entrez SP - 242 EP - 6 JF - Biomedical materials (Bristol, England) JO - Biomed Mater VL - 1 IS - 4 N2 - Blended films were prepared from a silk fibroin (SF) solution by adding a small amount of type I collagen (<5%). The mechanical properties of the wet films modified by collagen were improved obviously. The elongation at break reached 42%, and the smaller contact angles revealed that modified films had better hydrophilicity. 1% heparin was also added to modify the SF films to further improve the in vitro antithrombogenecity. The internal structure of the modified SF films was investigated with scanning electron microscopy, x-ray diffraction and Fourier transform infrared attenuated total reflection spectroscopy. The result indicates that the addition of a small amount of collagen and heparin did not change their conformation. SN - 1748-605X UR - https://www.unboundmedicine.com/medline/citation/18458412/Study_on_the_preparation_of_collagen_modified_silk_fibroin_films_and_their_properties_ DB - PRIME DP - Unbound Medicine ER -