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Angiostrongylus costaricensis egg antigen for the immunodiagnosis of abdominal angiostrongyliasis.
J Helminthol. 2008 Sep; 82(3):251-4.JH

Abstract

Angiostrongylus costaricensis is the aetiological agent of human abdominal angiostrongyliasis, a parasitic disease reported from the United States to Argentina, with a widespread occurrence of the nematode throughout Central and South America. This study assesses the performance of A. costaricensis eggs as antigen in an enzyme-linked immunosorbent assay (ELISA), for the determination of parasite-specific IgG1 antibodies. The specificity and the sensitivity of the method were 87% and 90.5%, respectively. Through this test it was possible to demonstrate a sharp and early decline in IgG1 antibody in serum samples taken from patients with histopathological diagnosis of abdominal angiostrongyliasis at different time points after surgical treatment. The present work demonstrated the usefulness of the egg antigen in the development of a specific diagnostic test for abdominal angiostrongylosis.

Authors+Show Affiliations

Department of Parasitology, University of Costa Rica, San Pedro/Mts. Oca, Costa Rica.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18462556

Citation

Mesén-Ramírez, P, et al. "Angiostrongylus Costaricensis Egg Antigen for the Immunodiagnosis of Abdominal Angiostrongyliasis." Journal of Helminthology, vol. 82, no. 3, 2008, pp. 251-4.
Mesén-Ramírez P, Abrahams-Sandí E, Fernández-Quesada K, et al. Angiostrongylus costaricensis egg antigen for the immunodiagnosis of abdominal angiostrongyliasis. J Helminthol. 2008;82(3):251-4.
Mesén-Ramírez, P., Abrahams-Sandí, E., Fernández-Quesada, K., & Morera, P. (2008). Angiostrongylus costaricensis egg antigen for the immunodiagnosis of abdominal angiostrongyliasis. Journal of Helminthology, 82(3), 251-4. https://doi.org/10.1017/S0022149X08982614
Mesén-Ramírez P, et al. Angiostrongylus Costaricensis Egg Antigen for the Immunodiagnosis of Abdominal Angiostrongyliasis. J Helminthol. 2008;82(3):251-4. PubMed PMID: 18462556.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Angiostrongylus costaricensis egg antigen for the immunodiagnosis of abdominal angiostrongyliasis. AU - Mesén-Ramírez,P, AU - Abrahams-Sandí,E, AU - Fernández-Quesada,K, AU - Morera,P, Y1 - 2008/05/08/ PY - 2008/5/9/pubmed PY - 2008/12/17/medline PY - 2008/5/9/entrez SP - 251 EP - 4 JF - Journal of helminthology JO - J Helminthol VL - 82 IS - 3 N2 - Angiostrongylus costaricensis is the aetiological agent of human abdominal angiostrongyliasis, a parasitic disease reported from the United States to Argentina, with a widespread occurrence of the nematode throughout Central and South America. This study assesses the performance of A. costaricensis eggs as antigen in an enzyme-linked immunosorbent assay (ELISA), for the determination of parasite-specific IgG1 antibodies. The specificity and the sensitivity of the method were 87% and 90.5%, respectively. Through this test it was possible to demonstrate a sharp and early decline in IgG1 antibody in serum samples taken from patients with histopathological diagnosis of abdominal angiostrongyliasis at different time points after surgical treatment. The present work demonstrated the usefulness of the egg antigen in the development of a specific diagnostic test for abdominal angiostrongylosis. SN - 0022-149X UR - https://www.unboundmedicine.com/medline/citation/18462556/Angiostrongylus_costaricensis_egg_antigen_for_the_immunodiagnosis_of_abdominal_angiostrongyliasis_ L2 - https://www.cambridge.org/core/product/identifier/S0022149X08982614/type/journal_article DB - PRIME DP - Unbound Medicine ER -