Tags

Type your tag names separated by a space and hit enter

Getting to guanine: mechanism and dynamics of charge separation and charge recombination in DNA revisited.
Photochem Photobiol Sci. 2008 May; 7(5):534-9.PP

Abstract

The mechanism and dynamics of charge separation and charge recombination in synthetic DNA hairpins possessing a stilbenedicarboxamide linker and a single guanine-cytosine base pair have been reinvestigated. The combination of femtosecond broad-band pump probe spectroscopy, nanosecond transient absorption experiments, and picosecond fluorescence decay measurements permits analysis of the formation and decay of the stilbene anion radical. Reversible hole injection resulting in the formation of the stilbene-adenine contact radical ion pair is found to occur on the picosecond time scale. The mechanism for charge separation across two or more base pairs is revised from single step superexchange to a multi-step process: hole injection followed by hole transport and hole trapping. The mechanism of charge recombination remains assigned to a superexchange process.

Authors+Show Affiliations

Department of Chemistry, Northwestern University, Evanston, IL 60201, USA. lewis@chem.northwestern.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

18465008

Citation

Lewis, Frederick D., et al. "Getting to Guanine: Mechanism and Dynamics of Charge Separation and Charge Recombination in DNA Revisited." Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology, vol. 7, no. 5, 2008, pp. 534-9.
Lewis FD, Zhu H, Daublain P, et al. Getting to guanine: mechanism and dynamics of charge separation and charge recombination in DNA revisited. Photochem Photobiol Sci. 2008;7(5):534-9.
Lewis, F. D., Zhu, H., Daublain, P., Sigmund, K., Fiebig, T., Raytchev, M., Wang, Q., & Shafirovich, V. (2008). Getting to guanine: mechanism and dynamics of charge separation and charge recombination in DNA revisited. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology, 7(5), 534-9. https://doi.org/10.1039/b719715b
Lewis FD, et al. Getting to Guanine: Mechanism and Dynamics of Charge Separation and Charge Recombination in DNA Revisited. Photochem Photobiol Sci. 2008;7(5):534-9. PubMed PMID: 18465008.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Getting to guanine: mechanism and dynamics of charge separation and charge recombination in DNA revisited. AU - Lewis,Frederick D, AU - Zhu,Huihe, AU - Daublain,Pierre, AU - Sigmund,Karsten, AU - Fiebig,Torsten, AU - Raytchev,Milen, AU - Wang,Qiang, AU - Shafirovich,Vladimir, Y1 - 2008/03/13/ PY - 2008/5/10/pubmed PY - 2008/7/10/medline PY - 2008/5/10/entrez SP - 534 EP - 9 JF - Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology JO - Photochem. Photobiol. Sci. VL - 7 IS - 5 N2 - The mechanism and dynamics of charge separation and charge recombination in synthetic DNA hairpins possessing a stilbenedicarboxamide linker and a single guanine-cytosine base pair have been reinvestigated. The combination of femtosecond broad-band pump probe spectroscopy, nanosecond transient absorption experiments, and picosecond fluorescence decay measurements permits analysis of the formation and decay of the stilbene anion radical. Reversible hole injection resulting in the formation of the stilbene-adenine contact radical ion pair is found to occur on the picosecond time scale. The mechanism for charge separation across two or more base pairs is revised from single step superexchange to a multi-step process: hole injection followed by hole transport and hole trapping. The mechanism of charge recombination remains assigned to a superexchange process. SN - 1474-905X UR - https://www.unboundmedicine.com/medline/citation/18465008/Getting_to_guanine:_mechanism_and_dynamics_of_charge_separation_and_charge_recombination_in_DNA_revisited_ L2 - https://doi.org/10.1039/b719715b DB - PRIME DP - Unbound Medicine ER -