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Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome.
Menopause. 2008 May-Jun; 15(3):524-9.M

Abstract

OBJECTIVE

Features of the metabolic syndrome such as abdominal adiposity, insulin resistance, and dyslipidemia develop with the transition from pre- to postmenopausal status in women. We investigated the effects of postmenopausal status on the prevalence of the metabolic syndrome according to years since menopause.

DESIGN

We studied 1,002 women, 618 premenopausal and 384 postmenopausal, who participated in annual health examinations at Anam Hospital in Seoul, Korea.

RESULTS

Using multivariate logistic regression analysis, we determined that postmenopausal status was an independent risk factor for the metabolic syndrome. Moreover, after controlling for age and body mass index, postmenopausal women had an increased risk of the metabolic syndrome (odds ratio, 2.93; 95% CI, 1.62-5.33) and the abnormalities of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause, then decreased. For its individual components, postmenopausal women with 5 to 9 years since menopause had the highest risk of high blood pressure; postmenopausal women with less than 5 years since menopause had an increased risk of abdominal obesity and high glucose. With 10 to 14 years since menopause, postmenopausal women had an increased risk of high triglycerides.

CONCLUSIONS

Postmenopausal status is an independent risk factor for the metabolic syndrome and all of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause. In addition, postmenopausal status has effects during different periods since menopause for each of these components.

Authors+Show Affiliations

Department of Obstetrics and Gynecology, College of Medicine, Korea University, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18467953

Citation

Cho, Geum Joon, et al. "Postmenopausal Status According to Years Since Menopause as an Independent Risk Factor for the Metabolic Syndrome." Menopause (New York, N.Y.), vol. 15, no. 3, 2008, pp. 524-9.
Cho GJ, Lee JH, Park HT, et al. Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome. Menopause. 2008;15(3):524-9.
Cho, G. J., Lee, J. H., Park, H. T., Shin, J. H., Hong, S. C., Kim, T., Hur, J. Y., Lee, K. W., Park, Y. K., & Kim, S. H. (2008). Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome. Menopause (New York, N.Y.), 15(3), 524-9. https://doi.org/10.1097/gme.0b013e3181559860
Cho GJ, et al. Postmenopausal Status According to Years Since Menopause as an Independent Risk Factor for the Metabolic Syndrome. Menopause. 2008 May-Jun;15(3):524-9. PubMed PMID: 18467953.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postmenopausal status according to years since menopause as an independent risk factor for the metabolic syndrome. AU - Cho,Geum Joon, AU - Lee,Jong Hyun, AU - Park,Hyun Tae, AU - Shin,Jung Ho, AU - Hong,Soon Cheol, AU - Kim,Tak, AU - Hur,Jun Young, AU - Lee,Kyu Wan, AU - Park,Yong Kyun, AU - Kim,Sun Haeng, PY - 2008/5/10/pubmed PY - 2008/10/8/medline PY - 2008/5/10/entrez SP - 524 EP - 9 JF - Menopause (New York, N.Y.) JO - Menopause VL - 15 IS - 3 N2 - OBJECTIVE: Features of the metabolic syndrome such as abdominal adiposity, insulin resistance, and dyslipidemia develop with the transition from pre- to postmenopausal status in women. We investigated the effects of postmenopausal status on the prevalence of the metabolic syndrome according to years since menopause. DESIGN: We studied 1,002 women, 618 premenopausal and 384 postmenopausal, who participated in annual health examinations at Anam Hospital in Seoul, Korea. RESULTS: Using multivariate logistic regression analysis, we determined that postmenopausal status was an independent risk factor for the metabolic syndrome. Moreover, after controlling for age and body mass index, postmenopausal women had an increased risk of the metabolic syndrome (odds ratio, 2.93; 95% CI, 1.62-5.33) and the abnormalities of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause, then decreased. For its individual components, postmenopausal women with 5 to 9 years since menopause had the highest risk of high blood pressure; postmenopausal women with less than 5 years since menopause had an increased risk of abdominal obesity and high glucose. With 10 to 14 years since menopause, postmenopausal women had an increased risk of high triglycerides. CONCLUSIONS: Postmenopausal status is an independent risk factor for the metabolic syndrome and all of its individual components. The risk for the metabolic syndrome increased up to 14 years since menopause. In addition, postmenopausal status has effects during different periods since menopause for each of these components. SN - 1072-3714 UR - https://www.unboundmedicine.com/medline/citation/18467953/Postmenopausal_status_according_to_years_since_menopause_as_an_independent_risk_factor_for_the_metabolic_syndrome_ L2 - https://doi.org/10.1097/gme.0b013e3181559860 DB - PRIME DP - Unbound Medicine ER -