TY - JOUR T1 - Determination of iodoacetic acid using liquid chromatography/electrospray tandem mass spectrometry. AU - Lau,Benjamin P-Y, AU - Becalski,Adam, PY - 2008/5/13/pubmed PY - 2008/7/24/medline PY - 2008/5/13/entrez SP - 1787 EP - 91 JF - Rapid communications in mass spectrometry : RCM JO - Rapid Commun Mass Spectrom VL - 22 IS - 12 N2 - A rapid analytical method based on liquid chromatography/tandem mass spectrometry (LC/MS/MS) using electrospray ionization in negative ion detection mode was developed for the analysis of underivatized iodoacetic acid in water. The method was applied to model reaction mixtures in the study of the formation of iodoacetic acid after chlorinated tap water was boiled in the presence of potassium iodide or iodized table salt. Samples can be directly analyzed by the LC/MS/MS system without extraction or chemical derivatization. Limit of detection was determined to be 0.3 microg/L (or 0.3 ng/mL) and limit of quantitation was about 1 microg/L (1 ng/mL). SN - 0951-4198 UR - https://www.unboundmedicine.com/medline/citation/18470871/Determination_of_iodoacetic_acid_using_liquid_chromatography/electrospray_tandem_mass_spectrometry_ L2 - https://doi.org/10.1002/rcm.3547 DB - PRIME DP - Unbound Medicine ER -