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Effect of a single intraoperative sub-Tenon injection of triamcinolone acetonide on the progression of diabetic retinopathy and visual outcomes after cataract surgery.
J Cataract Refract Surg 2008; 34(5):823-6JC

Abstract

PURPOSE

To assess the effect of a single intraoperative sub-Tenon injection of triamcinolone acetonide on the progression of diabetic retinopathy (DR), visual outcomes, and cystoid macular edema (CME) after cataract surgery.

SETTING

Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea.

METHODS

This prospective controlled study comprised 46 eyes of 23 diabetic patients. The control group comprised eyes not treated with a triamcinolone acetonide injection, and the triamcinolone group comprised contralateral eyes treated with a single posterior sub-Tenon injection of triamcinolone acetonide at the end of cataract surgery. The visual acuity, central macular thickness (CMT) by optical coherence tomography, and progression of DR were compared between the 2 groups.

RESULTS

One month postoperatively, the mean change in lines of best corrected visual acuity was significantly greater in the triamcinolone group (P = .045) and the mean change in CMT was significantly greater in the control group (P = .015). The incidence of CME was higher in the control group (P = 0.04). Scores for progression of DR at 6 months were not statistically significantly different between the 2 groups (P = 0.08).

CONCLUSIONS

A posterior sub-Tenon injection of triamcinolone acetonide lowered the incidence of CME after cataract surgery in diabetic patients, improved visual recovery, and reduced the amount of CMT increase in the short term (< or = 1 month postoperatively). However, triamcinolone acetonide did not affect DR progression over the 6-month follow-up.

Authors+Show Affiliations

Department of Ophthalmology and Visual Science, College of Medicine, Catholic University of Korea, Seoul, Korea.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18471640

Citation

Kim, Su-Young, et al. "Effect of a Single Intraoperative sub-Tenon Injection of Triamcinolone Acetonide On the Progression of Diabetic Retinopathy and Visual Outcomes After Cataract Surgery." Journal of Cataract and Refractive Surgery, vol. 34, no. 5, 2008, pp. 823-6.
Kim SY, Yang J, Lee YC, et al. Effect of a single intraoperative sub-Tenon injection of triamcinolone acetonide on the progression of diabetic retinopathy and visual outcomes after cataract surgery. J Cataract Refract Surg. 2008;34(5):823-6.
Kim, S. Y., Yang, J., Lee, Y. C., & Park, Y. H. (2008). Effect of a single intraoperative sub-Tenon injection of triamcinolone acetonide on the progression of diabetic retinopathy and visual outcomes after cataract surgery. Journal of Cataract and Refractive Surgery, 34(5), pp. 823-6. doi:10.1016/j.jcrs.2008.01.018.
Kim SY, et al. Effect of a Single Intraoperative sub-Tenon Injection of Triamcinolone Acetonide On the Progression of Diabetic Retinopathy and Visual Outcomes After Cataract Surgery. J Cataract Refract Surg. 2008;34(5):823-6. PubMed PMID: 18471640.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of a single intraoperative sub-Tenon injection of triamcinolone acetonide on the progression of diabetic retinopathy and visual outcomes after cataract surgery. AU - Kim,Su-Young, AU - Yang,Jiwook, AU - Lee,Young-Chun, AU - Park,Young-Hoon, PY - 2007/12/16/received PY - 2008/01/14/accepted PY - 2008/5/13/pubmed PY - 2008/6/17/medline PY - 2008/5/13/entrez SP - 823 EP - 6 JF - Journal of cataract and refractive surgery JO - J Cataract Refract Surg VL - 34 IS - 5 N2 - PURPOSE: To assess the effect of a single intraoperative sub-Tenon injection of triamcinolone acetonide on the progression of diabetic retinopathy (DR), visual outcomes, and cystoid macular edema (CME) after cataract surgery. SETTING: Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. METHODS: This prospective controlled study comprised 46 eyes of 23 diabetic patients. The control group comprised eyes not treated with a triamcinolone acetonide injection, and the triamcinolone group comprised contralateral eyes treated with a single posterior sub-Tenon injection of triamcinolone acetonide at the end of cataract surgery. The visual acuity, central macular thickness (CMT) by optical coherence tomography, and progression of DR were compared between the 2 groups. RESULTS: One month postoperatively, the mean change in lines of best corrected visual acuity was significantly greater in the triamcinolone group (P = .045) and the mean change in CMT was significantly greater in the control group (P = .015). The incidence of CME was higher in the control group (P = 0.04). Scores for progression of DR at 6 months were not statistically significantly different between the 2 groups (P = 0.08). CONCLUSIONS: A posterior sub-Tenon injection of triamcinolone acetonide lowered the incidence of CME after cataract surgery in diabetic patients, improved visual recovery, and reduced the amount of CMT increase in the short term (< or = 1 month postoperatively). However, triamcinolone acetonide did not affect DR progression over the 6-month follow-up. SN - 0886-3350 UR - https://www.unboundmedicine.com/medline/citation/18471640/Effect_of_a_single_intraoperative_sub_Tenon_injection_of_triamcinolone_acetonide_on_the_progression_of_diabetic_retinopathy_and_visual_outcomes_after_cataract_surgery_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0886-3350(08)00196-X DB - PRIME DP - Unbound Medicine ER -